Subclinical cardiotoxic effects of anthracyclines as assessed by magnetic resonance imaging—a pilot study

R Wassmuth, S Lentzsch, U Erdbruegger… - American heart …, 2001 - Elsevier
Background Anthracyclines are potent chemotherapeutics burdened by their cardiotoxicity.
So far no marker to detect early cardiac damage exists. We tested the ability of magnetic …

Identification of anthracycline cardiotoxicity: left ventricular ejection fraction is not enough

BW Eidem - Journal of the American Society of Echocardiography, 2008 - onlinejase.com
Anthracyclines have been used in cancer treatment since the late 1960s and are frequently
used in current pediatric and adult treatment protocols. This therapy is based on an …

Changes in left ventricular longitudinal strain with anthracycline chemotherapy in adolescents precede subsequent decreased left ventricular ejection fraction

JT Poterucha, S Kutty, RK Lindquist, L Li… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Pediatric cancer survivors who have been exposed to anthracycline (ANT)
chemotherapy are an ever increasing population at risk for premature cardiac disease …

Left ventricular myocardial deformation and mechanical dyssynchrony in children with normal ventricular shortening fraction after anthracycline therapy

Y Cheung, W Hong, GCF Chan, SJ Wong, S Ha - Heart, 2010 - heart.bmj.com
Objective The M-mode-derived left ventricular shortening fraction is incorporated into most of
the paediatric oncology protocols for monitoring of cardiotoxicity. This study tested the …

Abnormal myocardial strain indices in children receiving anthracycline chemotherapy

RH Pignatelli, P Ghazi, SCB Reddy, P Thompson… - Pediatric …, 2015 - Springer
Anthracycline chemotherapy (AC) is associated with impaired left ventricular (LV) systolic
function. LV ejection fraction (EF%) obtained by two-dimensional echocardiography is the …

Coronary microcirculation damage in anthracycline cardiotoxicity

C Galan-Arriola, JP Vílchez-Tschischke… - Cardiovascular …, 2022 - academic.oup.com
Aims The aim of this study was to study changes in coronary microcirculation status during
and after several cycles of anthracycline treatment. Methods and results Large-white male …

Myocardial 2D strain echocardiography and cardiac biomarkers in children during and shortly after anthracycline therapy for acute lymphoblastic leukaemia (ALL): a …

AMC Mavinkurve-Groothuis, KA Marcus… - European Heart …, 2013 - academic.oup.com
Aims The aim of this study was to investigate myocardial 2D strain echocardiography and
cardiac biomarkers in the assessment of cardiac function in children with acute …

Noninvasive evaluation of late anthracycline cardiac toxicity in childhood cancer survivors

MM Hudson, SN Rai, C Nunez, TE Merchant… - Journal of clinical …, 2007 - ascopubs.org
Purpose Childhood cancer survivors treated with anthracyclines and cardiac radiation are at
risk for late-onset cardiotoxicity. The purpose of this study was to delineate the relationship …

Anthracycline-related cardiotoxicity in childhood cancer survivors

SE Lipshultz, R Karnik, P Sambatakos… - Current opinion in …, 2014 - journals.lww.com
Despite major advances in cancer treatment, anthracycline-related cardiotoxicity remains a
major cause of morbidity and mortality in survivors of childhood cancer. Promising areas of …

Myocardial characterization using dual-energy CT in doxorubicin-induced DCM: comparison with CMR T1-mapping and histology in a rabbit model

YJ Hong, TK Kim, D Hong, CH Park, SJ Yoo… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: This study sought to evaluate whether patterns of myocardial change in
doxorubicin-induced dilated cardiomyopathy determined using dual-energy computed …