Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage with fluid-structure interaction analysis

R Fang, Z Wang, X Zhao, J Wang, Y Li, Y Zhang… - Computers in biology …, 2022 - Elsevier
The majority of cardioembolic strokes in patients with non-valvular atrial fibrillation (NVAF)
are resulted from clot formation in the left atrial appendage (LAA). Current stroke risk …

[HTML][HTML] Evaluation of stroke risk in patients with atrial fibrillation using morphological and hemodynamic characteristics

L Wang, Z Wang, R Fang, ZY Li - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Background: It is well known that the thrombus triggering stroke in patients with atrial
fibrillation (AF) mainly comes from the left atrial appendage (LAA). This study aims to …

The impact of left atrium appendage morphology on stroke risk assessment in atrial fibrillation: a computational fluid dynamics study

A Masci, L Barone, L Dedè, M Fedele, C Tomasi… - Frontiers in …, 2019 - frontiersin.org
Atrial fibrillation (AF) carries out a 5-fold increase in stroke risk, related to embolization of
thrombi clotting in left atrium (LA). Left atrial appendage (LAA) is the site with the highest …

Subject-specific factors affecting particle residence time distribution of left atrial appendage in atrial fibrillation: A computational model-based study

S Sanatkhani, S Nedios, PG Menon… - Frontiers in …, 2023 - frontiersin.org
Background Atrial fibrillation (AF) is a prevalent arrhythmia, that causes thrombus formation,
ordinarily in the left atrial appendage (LAA). The conventional metric of stroke risk …

Slow blood-flow in the left atrial appendage is associated with stroke in atrial fibrillation patients

N Paliwal, HC Park, Y Mao, SJ Hong, Y Lee… - Heliyon, 2024 - cell.com
Background Atrial fibrillation (AF) patients are at high risk of stroke with∼ 90% clots
originating from the left atrial appendage (LAA). Clinical understanding of blood-flow based …

Correlation between LAA morphological features and computational fluid dynamics analysis for non-valvular atrial fibrillation patients

BM Fanni, K Capellini, M Di Leonardo, A Clemente… - Applied Sciences, 2020 - mdpi.com
The left atrial appendage (LAA) is a complex cardiovascular structure which can yield to
thrombi formation in patients with non-valvular atrial fibrillation (AF). The study of LAA fluid …

Impact of left atrial appendage location on risk of thrombus formation in patients with atrial fibrillation

R Fang, Y Li, Y Zhang, Q Chen, Q Liu, Z Li - Biomechanics and Modeling …, 2021 - Springer
Most strokes in patients with atrial fibrillation (AF) are thought to arise from thrombus
formation in the left atrial appendage (LAA). Assessing the hemodynamics in LAA and left …

Stroke risk evaluation for patients with atrial fibrillation: Insights from left atrial appendage

R Fang, Y Li, J Wang, Z Wang, J Allen… - Frontiers in …, 2022 - frontiersin.org
Left atrial appendage (LAA) is believed to be a common site of thrombus formation in
patients with atrial fibrillation (AF). However, the commonly-applied stroke risk stratification …

Joint analysis of morphological parameters and in silico haemodynamics of the left atrial appendage for thrombogenic risk assessment

MI Pons, J Mill, A Fernandez-Quilez… - Journal of …, 2022 - Wiley Online Library
Background. Atrial fibrillation (AF) is considered the most common human arrhythmia. In
nonvalvular AF, around 99% of thrombi are formed in the left atrial appendage (LAA) …

Computational fluid dynamic analysis of the left atrial appendage to predict thrombosis risk

GM Bosi, A Cook, R Rai, LJ Menezes… - Frontiers in …, 2018 - frontiersin.org
During Atrial Fibrillation (AF) more than 90% of the left atrial thrombi responsible for
thromboembolic events originate in the left atrial appendage (LAA), a complex small sac …