Safety and feasibility of continuous infusion of remifentanil in the neurosurgical intensive care unit

LB Tipps, WM Coplin, KR Murry, DH Rhoney - Neurosurgery, 2000 - journals.lww.com
OBJECTIVE: Remifentanil is a selective μ-opioid agonist with a context-sensitive half-time of
3 to 5 minutes, independent of dose or administration duration. Other desirable effects …

Remifentanil: a review of its analgesic and sedative use in the intensive care unit

AJ Battershill, GM Keating - Drugs, 2006 - Springer
Summary Abstract Remifentanil (Ultiva™), a 4-anilidopiperidine derivative of fentanyl, is an
ultra-short-acting μ-opioid receptor agonist indicated to provide analgesia and sedation in …

Continuous remifentanil for pediatric neurosurgery patients

JW German, R Aneja, C Heard, M Dias - Pediatric neurosurgery, 2000 - karger.com
Objective: Remifentanil hydrochloride is a new titratable opioid agonist with rapid onset and
offset of action. We present 2 cases of intracranial mass lesions in whom remifentanil was …

Remifentanil

J Cohen, D Royston - Current opinion in critical care, 2001 - journals.lww.com
Remifentanil is an opioid with a unique pharmacokinetic profile. Its metabolism by
nonspecific esterases results in rapid and uniform clearance leading to highly predictable …

The effects of remifentanil on endotracheal suctioning-induced increases in intracranial pressure in head-injured patients

M Leone, J Albanese, X Viviand, F Garnier… - Anesthesia & …, 2004 - journals.lww.com
IMPLICATIONS: Remifentanil bolus in severe head trauma patients in the intensive care unit
induces an increase in intracranial pressure related to a decrease in mean arterial blood …

Remifentanil and the brain

V Fodale, D Schifilliti, C Pratico… - Acta …, 2008 - Wiley Online Library
Background and aim: Remifentanil is an ultra‐short‐acting opioid, increasingly used today
in neuroanesthesia and neurointensive care. Its characteristics make remifentanil a …

Section Review: Central & Peripheral Nervous System: Remifentanil and anaesthesia for the future

MK James - Expert Opinion on Investigational Drugs, 1994 - Taylor & Francis
Current trends toward outpatient surgery have created a demand for shorter acting
anaesthetic agents. Such agents not only provide the anaesthetist with rapid patient …

Effect of remifentanil on intracranial pressure and cerebral blood flow velocity in patients with head trauma

K Engelhard, W Reeker, E Kochs… - Acta anaesthesiologica …, 2004 - Wiley Online Library
Background: Remifentanil, an ultra‐short‐acting opioid, is used as an on‐top analgesic in
head trauma patients during transient painful procedures, eg endotracheal suctioning …

Remifentanil: a review of its use during the induction and maintenance of general anaesthesia

LJ Scott, CM Perry - Drugs, 2005 - Springer
Remifentanil (Ultiva™), a fentanyl derivative, is an ultra-short acting, nonspecific esterase-
metabolised, selective μ-opioid receptor agonist, with a pharmacodynamic profile typical of …

The place for short-acting opioids: special emphasis on remifentanil

W Wilhelm, S Kreuer - Critical Care, 2008 - Springer
Pain is among the worst possible experiences for the critically ill. Therefore, nearly all
intensive care patients receive some kind of pain relief, and opioids are most frequently …