Morphine is the most widely used compound among narcotic analgesics and remains the
gold standard when the effects of other analgetic drugs are compared. Apart from its …

The purposes of this comprehensive review are: first. to introduce the reader to the historical
and current uses for morphine and to give a brief outline of the relevant physicochemical …

Morphine derived from Papaver somniferum is commonly used as an analgesic compound
for pain relief. It is now accepted that endogenous morphine, structurally identical to vegetal …

Le sort de la morphine et de ses succedanes synth6tiques dans l'organisme humain et
animal, la connaissance du groupe chimique qui exerce une action hautement selective sur …

The emetic potencies of morphine and its metabolite morphine 6-glucuronide have been
determined in the ferret by constructing dose-response curves for mean total retches and …

New morphine metabolites in the urine of guinea pigs, rats, rabbits, cats, monkeys, and
humans were isolated with column chromatography, solvent extraction, and TLC and …

Morphine-6 beta-glucuronide is a major metabolite of morphine with potent analgesic
actions. To define more fully the importance of this compound in morphine action, we have …

An opioid is a chemical that binds to opioid receptors, which are widely distributed in the
central and peripheral nervous system and gastrointestinal tract. The different effects elicited …

To understand the potent analgesic action of morphine-6-glucuronide (M-6-G), which was
reported previously to be a minor metabolite of morphine in several mammalian species, the …

The metabolites of morphine, morphine-6-glucuronide (M6G) and morphine-3-glucuronide
(M3G), have been extensively studied for their contribution to clinical effects following …