Assessment of diffuse myocardial fibrosis in rats using small-animal Look-Locker inversion recovery T1 mapping

DR Messroghli, S Nordmeyer, T Dietrich… - Circulation …, 2011 - Am Heart Assoc
Background—The concentration of gadopentetate dimeglumine in myocardium and blood
can be assessed from T1 measurements and can be used to calculate the extracellular …

[HTML][HTML] Histological Validation of measurement of diffuse interstitial myocardial fibrosis by myocardial extravascular volume fraction from Modified Look-Locker …

CM de Ravenstein, C Bouzin, S Lazam, J Boulif… - Journal of …, 2015 - Elsevier
Abstract Background Gadolinium (Gd) Extracellular volume fraction (ECV) by
Cardiovascular Magnetic Resonance (CMR) has been proposed as a non-invasive method …

[HTML][HTML] Diffuse myocardial fibrosis evaluation using cardiac magnetic resonance T1 mapping: sample size considerations for clinical trials

S Liu, J Han, MS Nacif, J Jones, N Kawel… - Journal of …, 2012 - Elsevier
Background Cardiac magnetic resonance (CMR) T1 mapping has been used to characterize
myocardial diffuse fibrosis. The aim of this study is to determine the reproducibility and …

Gadolinium-enhanced magnetic resonance imaging for detection and quantification of fibrosis in human myocardium in vitro

E Kehr, M Sono, SS Chugh… - The international journal of …, 2008 - Springer
Background The availability of a non-invasive test to detect and quantify interstitial and
replacement fibrosis would be a useful advance for evaluation of cardiac therapies that …

Histological validation of cardiac magnetic resonance T1 mapping for detecting diffuse myocardial fibrosis in diabetic rabbits

M Zeng, N Zhang, Y He, Z Wen, Z Wang… - Journal of Magnetic …, 2016 - Wiley Online Library
Purpose To pathologically verify the correlation between native T1 mapping, postcontrast T1
mapping, and extracellular volume fraction (ECV) and myocardial diffuse fibrosis, as …

[HTML][HTML] Myocardial extravascular extracellular volume fraction measurement by gadolinium cardiovascular magnetic resonance in humans: slow infusion versus …

EB Schelbert, SM Testa, CG Meier, WJ Ceyrolles… - Journal of …, 2011 - Elsevier
Background Myocardial extravascular extracellular volume fraction (Ve) measures quantify
diffuse fibrosis not readily detectable by conventional late gadolinium (Gd) enhancement …

[HTML][HTML] Assessment of myocardial fibrosis in mice using a T2*-weighted 3D radial magnetic resonance imaging sequence

BJ van Nierop, NAM Bax, JL Nelissen, F Arslan… - PloS one, 2015 - journals.plos.org
Background Myocardial fibrosis is a common hallmark of many diseases of the heart. Late
gadolinium enhanced MRI is a powerful tool to image replacement fibrosis after myocardial …

[HTML][HTML] Single bolus versus split dose gadolinium administration in extra-cellular volume calculation at 3 Tesla

AK McDiarmid, PP Swoboda, B Erhayiem… - Journal of …, 2015 - Springer
Background Diffuse myocardial fibrosis may be quantified with cardiovascular magnetic
resonance (CMR) by calculating extra-cellular volume (ECV) from native and post-contrast …

Myocardial tissue characterization using magnetic resonance noncontrast t1 mapping in hypertrophic and dilated cardiomyopathy

S Dass, JJ Suttie, SK Piechnik, VM Ferreira… - Circulation …, 2012 - Am Heart Assoc
Background—Noncontrast magnetic resonance T1 mapping reflects a composite of both
intra-and extracellular signal. We hypothesized that noncontrast T1 mapping can …

[HTML][HTML] MR extracellular volume mapping and non-contrast T1ρ mapping allow early detection of myocardial fibrosis in diabetic monkeys

Y Zhang, W Zeng, W Chen, Y Chen, T Zhu, J Sun… - European …, 2019 - Springer
Objective To detect diffuse myocardial fibrosis in different severity levels of left ventricular
diastolic dysfunction (DD) in spontaneous type 2 diabetes mellitus (T2DM) rhesus monkeys …