Characterizing left atrial appendage functions in sinus rhythm and atrial fibrillation using computational models

LT Zhang, M Gay - Journal of biomechanics, 2008 - Elsevier
Clinical studies show that the left atrial appendage, a blind-ended structure that is attached
to the left atrium, may be the cause of 90% of atrial thrombi in atrial fibrillation (abnormal …

Left atrial appendage shape impacts on the left atrial flow hemodynamics: a numerical hypothesis generating study on two cases

L Alinezhad, F Ghalichi, M Ahmadlouydarab… - Computer Methods and …, 2022 - Elsevier
Background and objectives The left atrial appendage (LAA) is the most common region for
thrombus formation in atrial fibrillation (AF). Morphological parameters such as shape, size …

Sensitivity analysis of geometrical parameters to study haemodynamics and thrombus formation in the left atrial appendage

G García‐Isla, AL Olivares, E Silva… - … journal for numerical …, 2018 - Wiley Online Library
The left atrial appendage (LAA) is a complex and heterogeneous protruding structure of the
left atrium (LA). In atrial fibrillation patients, it is the location where 90% of the thrombi are …

[HTML][HTML] Effect of the alterations in contractility and morphology produced by atrial fibrillation on the thrombosis potential of the left atrial appendage

D Vella, A Monteleone, G Musotto, GM Bosi… - … in Bioengineering and …, 2021 - frontiersin.org
Atrial fibrillation (AF) is a common arrhythmia mainly affecting the elderly population, which
can lead to serious complications such as stroke, ischaemic attack and vascular dementia …

Numerical analysis of hemodynamic changes in the left atrium due to atrial fibrillation

R Koizumi, K Funamoto, T Hayase, Y Kanke… - Journal of …, 2015 - Elsevier
Atrial fibrillation (AF) disrupts movement of the left atrium (LA) and worsens the vital
prognosis by causing thromboembolism. Ultrasound Doppler measurement, phase-contrast …

Impact of left atrial appendage location on risk of thrombus formation in patients with atrial fibrillation

R Fang, Y Li, Y Zhang, Q Chen, Q Liu, Z Li - Biomechanics and Modeling …, 2021 - Springer
Most strokes in patients with atrial fibrillation (AF) are thought to arise from thrombus
formation in the left atrial appendage (LAA). Assessing the hemodynamics in LAA and left …

[HTML][HTML] Inversion of left atrial appendage will cause compressive stresses in the tissue: Simulation study of potential therapy

S Pasta, JM Guccione, GS Kassab - Journal of Personalized Medicine, 2022 - mdpi.com
In atrial fibrillation (AF), thromboembolic events can result from the particular conformation of
the left atrial appendage (LAA) bearing increased clot formation and accumulation. Current …

[HTML][HTML] Numerical study of the risk of thrombosis in the left atrial appendage of chicken wing shape in atrial fibrillation

J Yang, C Song, H Ding, M Chen, J Sun… - Frontiers in …, 2022 - frontiersin.org
Atrial fibrillation (AF) is a common and life-threatening disease. For the patients with atrial
fibrillation, more than 90% of the thrombi are formed in the left atrial appendage (LAA) …

Computational modeling of hemodynamics and risk of thrombosis in the left atrial appendage using patient-specific blood viscosity and boundary conditions at the …

Z Zhang, J Zhu, M Wu, M Neidlin, WT Wu… - … and Modeling in …, 2023 - Springer
Hemodynamics play a vital role for the risk of thrombosis in the left atrial appendage (LAA)
and left atrium (LA) for patients with atrial fibrillation. Accurate prediction of hemodynamics in …

[HTML][HTML] The role of patient-specific morphological features of the left atrial appendage on the thromboembolic risk under atrial fibrillation

G Musotto, A Monteleone, D Vella… - Frontiers in …, 2022 - frontiersin.org
Background A large majority of thrombi causing ischemic complications under atrial
fibrillation (AF) originate in the left atrial appendage (LAA), an anatomical structure departing …