Evaluation of Diffuse Myocardial Fibrosis in Heart Failure With Cardiac Magnetic Resonance Contrast-Enhanced T1 Mapping

L Iles, H Pfluger, A Phrommintikul, J Cherayath… - Journal of the American …, 2008 - jacc.org
Objectives: The purpose of this study was to investigate a noninvasive method for
quantifying diffuse myocardial fibrosis with cardiac magnetic resonance imaging (CMRI) …

[HTML][HTML] Diffuse myocardial fibrosis evaluation using cardiac magnetic resonance T1 mapping: sample size considerations for clinical trials

S Liu, J Han, MS Nacif, J Jones, N Kawel… - Journal of …, 2012 - Elsevier
Background Cardiac magnetic resonance (CMR) T1 mapping has been used to characterize
myocardial diffuse fibrosis. The aim of this study is to determine the reproducibility and …

Assessment of myocardial fibrosis with cardiovascular magnetic resonance

N Mewton, CY Liu, P Croisille, D Bluemke… - Journal of the American …, 2011 - jacc.org
Diffuse interstitial or replacement myocardial fibrosis is a common feature of a broad variety
of cardiomyopathies. Myocardial fibrosis leads to impaired cardiac diastolic and systolic …

Histological validation of cardiac magnetic resonance analysis of regional and diffuse interstitial myocardial fibrosis

LM Iles, AH Ellims, H Llewellyn, JL Hare… - European Heart …, 2015 - academic.oup.com
Aim Myocardial fibrosis is fundamental in the pathogenesis of heart failure. Late gadolinium
enhancement (LGE) with cardiac magnetic resonance (CMR) imaging is commonly …

Assessment of myocardial fibrosis with T1 mapping MRI

RJ Everett, CG Stirrat, SIR Semple, DE Newby… - Clinical radiology, 2016 - Elsevier
Myocardial fibrosis can arise from a range of pathological processes and its presence
correlates with adverse clinical outcomes. Cardiac magnetic resonance (CMR) can provide …

Cardiac MRI: a central prognostic tool in myocardial fibrosis

B Ambale-Venkatesh, JAC Lima - Nature Reviews Cardiology, 2015 - nature.com
Fibrotic remodelling of the extracellular matrix is a healing mechanism necessary
immediately after myocardial injury. However, prolonged increase in myocardial fibrotic …

Equilibrium contrast cardiovascular magnetic resonance for the measurement of diffuse myocardial fibrosis: preliminary validation in humans

AS Flett, MP Hayward, MT Ashworth, MS Hansen… - Circulation, 2010 - Am Heart Assoc
Background—Diffuse myocardial fibrosis is a final end point in most cardiac diseases. It is
missed by the cardiovascular magnetic resonance (CMR) late gadolinium enhancement …

T1 Mapping in cardiomyopathy at cardiac MR: comparison with endomyocardial biopsy

CT Sibley, RA Noureldin, N Gai, MS Nacif, S Liu… - Radiology, 2012 - pubs.rsna.org
Purpose To determine the utility of cardiac magnetic resonance (MR) T1 mapping for
quantification of diffuse myocardial fibrosis compared with the standard of endomyocardial …

Native T1 mapping and extracellular volume mapping for the assessment of diffuse myocardial fibrosis in dilated cardiomyopathy

S Nakamori, K Dohi, M Ishida, Y Goto… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives: The purpose of this study was to examine the histological correlation of native
myocardial T1 and extracellular volume fraction (ECV) measurement at 3-T for the …

Diffuse Myocardial Fibrosis Evaluated by Post-Contrast T1 Mapping Correlates With Left Ventricular Stiffness

AH Ellims, JA Shaw, D Stub, LM Iles, JL Hare… - Journal of the American …, 2014 - jacc.org
Objectives: The purpose of this study was to use cardiac magnetic resonance (CMR)
imaging and invasive left ventricular (LV) pressure-volume (PV) measurements to explore …