This brief review describes the pathogenesis of the adult respiratory distress syndrome
(ARDS) and the rationale for surfactant replacement therapy. In four animal models in which …

Inactivation of pulmonary surfactant may be important in acute lung injury and acute
respiratory distress syndrome. Treatment of surfactant dysfunction by instilling exogenous …

Introduction: Available literature suggests that the advantage of animal-derived surfactants
over first-generation synthetic agents derives from the presence of surface-active proteins …

Pulmonary surfactant is a highly surface-active material that lines the alveolar surface of the
lung. The major function of pulmonary surfactant is the reduction of surface tension at the air …

Pulmonary surfactant is a complex and highly surface-active material necessary for
sustaining life by lowering surface tension to assist alveolar expansion, allowing gas …

Purpose. The aim of this prospectively designed study was to investigate the efficacy of
surfactant (S) for acute respiratory distress syndrome (ARDS) in children. Materials and …

Background: Exogenous surfactant is an undisputed treatment for neonatal respiratory
distress syndrome but its efficacy is highly dependent on the treatment strategy. International …

Clinical trials have evaluated the overall efficacy of surfactant therapy, as well as the relative
efficacy of different surfactant preparations, the optimal timing of administration and the …

Surfactant for respiratory distress syndrome: are there impo... : Current Opinion in Pediatrics
Surfactant for respiratory distress syndrome: are there important clinical differences among …