Surfactant therapies for pediatric and neonatal ARDS: ESPNIC expert consensus opinion for future research steps
D De Luca, P Cogo, MC Kneyber, P Biban, MG Semple… - Critical Care, 2021 - Springer
Pediatric (PARDS) and neonatal (NARDS) acute respiratory distress syndrome have
different age-specific characteristics and definitions. Trials on surfactant for ARDS in children …
different age-specific characteristics and definitions. Trials on surfactant for ARDS in children …
Adult respiratory distress syndrome and artificial surfactant replacement in the pediatric patient
F PEREZ-BENAVIDES, E RIFF… - Pediatric emergency …, 1995 - journals.lww.com
Adult respiratory distress syndrome (ARDS) frequently develops after near-drowning, smoke
inhalation, burns, blunt trauma to chest, and overwhelming sepsis. Surfactant depletion …
inhalation, burns, blunt trauma to chest, and overwhelming sepsis. Surfactant depletion …
Severe neonatal respiratory distress syndrome treated with the isolated phospholipid fraction of natural surfactant
G Noack, P Berggren, T Curstedt, G Grossmann… - Acta …, 1987 - Wiley Online Library
Ten newborn infants (795–1680 g) with severe respiratory distress syndrome (RDS) were
treated with the isolated phospholipid fraction of bovine or porcine surfactant, which was …
treated with the isolated phospholipid fraction of bovine or porcine surfactant, which was …
Comparison of clinical responses to natural and synthetic surfactants
M Rollins, J Jenkins, R Tubman, C Corkey, D Wilson - 1993 - degruyter.com
In recent years both natural and synthetic surfactants have been shown to be effective in
reducing mortality and morbidity in neonates with respiratory distress syndrome [1, 2, 4—24] …
reducing mortality and morbidity in neonates with respiratory distress syndrome [1, 2, 4—24] …
Novel approaches to surfactant administration
S Gupta, SM Donn - Critical Care Research and Practice, 2012 - Wiley Online Library
Surfactant replacement therapy has been the mainstay of treatment for preterm infants with
respiratory distress syndrome for more than twenty years. For the most part, surfactant is …
respiratory distress syndrome for more than twenty years. For the most part, surfactant is …
Surfactant replacement therapy: an update on applications
SA Dekowski, RB Holtzman - Pediatric Clinics of North America, 1998 - Elsevier
Surfactant replacement therapy has been shown to be an effective and often life-saving
treatment for newborn infants with respiratory distress syndrome (RDS). Since the …
treatment for newborn infants with respiratory distress syndrome (RDS). Since the …
[HTML][HTML] A recipe for a good clinical pulmonary surfactant
J Pérez-Gil - biomedical journal, 2022 - Elsevier
The lives of thousands premature babies have been saved along the last thirty years thanks
to the establishment and consolidation of pulmonary surfactant replacement therapies …
to the establishment and consolidation of pulmonary surfactant replacement therapies …
Designer surfactants: the next generation in surfactant replacement
BA Holm, AJ Waring - Clinics in perinatology, 1993 - Elsevier
Exogenous surfactant replacement mixtures currently used for the prevention and treatment
of neonatal respiratory distress syndrome are either obtained from mammalian lungs or are …
of neonatal respiratory distress syndrome are either obtained from mammalian lungs or are …
Effects of ventilation strategies on the efficacy of exogenous surfactant therapy in a rabbit model of acute lung injury
Y ITO, SEE MANWELL, CL KERR… - American journal of …, 1998 - atsjournals.org
We evaluated the effects of various ventilation strategies on the efficacy of exogenous
surfactant therapy in lung-injured adult rabbits. Lung injury was induced by repetitive whole …
surfactant therapy in lung-injured adult rabbits. Lung injury was induced by repetitive whole …
Strategies to protect surfactant and enhance its activity
The knowledge about surfactant biology is now deeper and recent research has allowed to
clarify its role in several human lung disorders. The balance between surfactant production …
clarify its role in several human lung disorders. The balance between surfactant production …