Background and objective The neuropathology of amyotrophic lateral sclerosis (ALS)
follows a regional distribution pattern in the brain with four stages. Using diffusion tensor …

Objective: The potential of magnetic resonance imaging (MRI) as a technical biomarker for
cerebral microstructural alterations in neurodegenerative diseases is under investigation. In …

Objective Neuropathological studies in amyotrophic lateral sclerosis (ALS) have shown a
dissemination in a regional sequence in four anatomically defined patterns. The aim of this …

OBJECTIVE: Aim of present study was to evaluate changes in diffusion tensor imaging (DTI)
parameters in the whole brain of 28 patients with amyotrophic lateral sclerosis (ALS) …

Numerous neuroimaging studies in amyotrophic lateral sclerosis (ALS) have reported links
between structural changes and clinical data; however phenotypic and disease course …

Background Amyotrophic lateral sclerosis (ALS) is characterized by pronounced clinical
heterogeneity in terms of onset and disease progression. Widespread changes in white …

Background This study was performed to assess changes in diffusion tensor imaging (DTI)
over time in patients with amyotrophic lateral sclerosis (ALS). Methods We performed DTI in …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. However, no reliable
biomarkers have been identified to represent the clinical status. This study aimed to …

Abstract Background and Objective Diffusion tensor imaging (DTI) can be used to tract-wise
map correlates of the sequential disease progression and, therefore, to assess disease …

Objective Damage to the cerebral tissue structural connectivity associated with amyotrophic
lateral sclerosis (ALS), which extends beyond the motor pathways, can be visualised by …