Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
A Astrup, S Rössner, L Van Gaal, A Rissanen… - The Lancet, 2009 - thelancet.com
Background The frequency of obesity has risen dramatically in recent years but only few
safe and effective drugs are currently available. We assessed the effect of liraglutide on …
safe and effective drugs are currently available. We assessed the effect of liraglutide on …
A randomized, controlled trial of 3.0 mg of liraglutide in weight management
X Pi-Sunyer, A Astrup, K Fujioka… - … England Journal of …, 2015 - Mass Medical Soc
Background Obesity is a chronic disease with serious health consequences, but weight loss
is difficult to maintain through lifestyle intervention alone. Liraglutide, a glucagon-like …
is difficult to maintain through lifestyle intervention alone. Liraglutide, a glucagon-like …
Liraglutide for weight management: a critical review of the evidence
Objective To review the efficacy, safety, and clinical applicability of liraglutide for weight
management from phase III clinical trials. Methods A search of the English language …
management from phase III clinical trials. Methods A search of the English language …
Liraglutide: a new option for the treatment of obesity
WA Nuffer, JM Trujillo - Pharmacotherapy: The Journal of …, 2015 - Wiley Online Library
Obesity continues to pose a major public health risk to the United States and across the
world, with an estimated one‐third of adult Americans being defined as obese. Obesity …
world, with an estimated one‐third of adult Americans being defined as obese. Obesity …
Efficacy of liraglutide for weight loss among patients with type 2 diabetes: the SCALE diabetes randomized clinical trial
MJ Davies, R Bergenstal, B Bode, RF Kushner… - Jama, 2015 - jamanetwork.com
Importance Weight loss of 5% to 10% can improve type 2 diabetes and related
comorbidities. Few safe, effective weight-management drugs are currently available …
comorbidities. Few safe, effective weight-management drugs are currently available …
Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
Objective: Having demonstrated short-term weight loss with liraglutide in this group of obese
adults, we now evaluate safety/tolerability (primary outcome) and long-term efficacy for …
adults, we now evaluate safety/tolerability (primary outcome) and long-term efficacy for …
Effects of liraglutide on visceral and ectopic fat in adults with overweight and obesity at high cardiovascular risk: a randomised, double-blind, placebo-controlled …
IJ Neeland, SP Marso, CR Ayers, B Lewis… - The lancet Diabetes & …, 2021 - thelancet.com
Background Visceral and ectopic fat are key drivers of adverse cardiometabolic outcomes in
obesity. We aimed to evaluate the effects of injectable liraglutide 3· 0 mg daily on body fat …
obesity. We aimed to evaluate the effects of injectable liraglutide 3· 0 mg daily on body fat …
An evaluation of liraglutide including its efficacy and safety for the treatment of obesity
CH Lin, L Shao, YM Zhang, YJ Tu, Y Zhang… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: The prevalence of obesity is increasing worldwide and associated conditions,
particularly type 2 diabetes mellitus (T2DM), also show increasing prevalence. Lifestyle …
particularly type 2 diabetes mellitus (T2DM), also show increasing prevalence. Lifestyle …
Efficacy and safety of liraglutide for overweight adult patients with type 1 diabetes and insufficient glycaemic control (Lira-1): a randomised, double-blind, placebo …
TF Dejgaard, CS Frandsen, TS Hansen… - The lancet Diabetes & …, 2016 - thelancet.com
Background The combination of insulin and glucagon-like peptide-1 (GLP-1) receptor
agonist therapy improves glycaemic control, induces weight loss, and reduces insulin dose …
agonist therapy improves glycaemic control, induces weight loss, and reduces insulin dose …
Tolerability of nausea and vomiting and associations with weight loss in a randomized trial of liraglutide in obese, non-diabetic adults
Background: Liraglutide 3.0 mg, with diet and exercise, produced substantial weight loss
over 1 year that was sustained over 2 years in obese non-diabetic adults. Nausea was the …
over 1 year that was sustained over 2 years in obese non-diabetic adults. Nausea was the …