The pharmacokinetics of fentanyl are complicated by an additional increase in plasma
concentration during the elimination phase of the drug. We have confirmed that fentanyl is …

Fentanyl kinetics was studied in two groups of six patients, one group undergoing surgery
with and one without cardiopulmonary bypass; the latter served as the controls. Plasma …

The pharmacokinetics of fentanyl and alfentanil were compared by the simultaneous iv
administration of both drugs, measurement of plasma concentrations and compartmental …

Relationships between plasma concentrations of fentanyl and is analgesic, respiratory and
cardiovascular effects were determined in unanesthetized dogs. To avoid drug interactions …

Thirty patients undergoing major abdominal gynaecological surgery were anaesthetized
with a standard technique including nitrous oxide in oxygen and myoneural blockade. The …

The pharmacokinetics following a bolus injection of fentanyl 60 μg kg− 1 as the sole
anaesthetic in five patients undergoing cardiac surgery are described. Before …

Our study investigated the effects of moderate doses of fentanyl and sufentanil versus high-
dose sufentanil on cerebral hemodynamics by using transcranial Doppler ultrasonography …

The influence of phenobarbitone anaesthesia on blood flow (CBF) and oxygen consumption
(CMRo2) was evaluated in the rat brain, using a method that quantitatively measures CBF in …

Background The relative respiratory effects of fentanyl and remifentanil, administered as iv
bolus, have not previously been studied. We determined what remifentanil bolus dose gave …

The ability of a simple infusion scheme for fentanyl to achieve and maintain one of two target
concentrations of fentanyl in plasma was studied in 17 patients having cardiac surgery that …