Cerebral blood flow was measured by means of a 10‐channel cerebrograph in anesthe‐
tised patients before and during 2% enfluranc. This investigation was carried out after …

Conventional compartmental models of the uptake and distribution of inhaled anaesthetics
assume that blood moves from lungs to tissues and from tissues back to lungs in zero time …

Fentanyl kinetics were studied in patients with cirrhosis and in patients with normal hepatic
and renal function undergoing surgery under general anaesthesia, the latter group served …

Two recent studies have examined the pharmacokinetics of sevoflurane in adults. Lu et
al.(Pharmacokinetics of sevoflurane uptake into the brain and body, Anaesthesia 2003; 58 …

Background Analgesia and sedation have been achieved noninvasively by fentanyl
administration through the oral and nasal mucosa. In theory, the transmucosal bioavailability …

The effects of large doses of morphinomimetics on the cerebral circulation were studied in
12 normal subjects (fentanyl 16 microgram/kg in 6 patients and fentathienyl 1.9 …

Respiratory, function following single bolus doses as well as continuous infusions of
epidural fentanyl were studied in 21 patients. Respiratory rate decreased significantly and …

Background: In clinical neuroanaesthesia, the increase in cerebral blood flow (CBF) and
intracranial pressure caused by the cerebral vasodilative effects of an inhalational …

Alfentanil is reported to increase intracranial pressure (ICP) after neurotrauma. A direct
cerebral vasodilator effect has been postulated. We studied 17 Sprague-Dawley rats …

The effects of a mixture of diazepam and fentanyl on cerebral blood flow (cbf) and cerebral
metabolism of oxygen (CMRo 2) were studied in eight normal subjects and 13 patients with …