In many European countries the use of opioids for long-term treatment of nonmalignant pain
has dramatically increased during the last decade in order to improve the patient's quality of …

Driving has been regarded as an activity of daily living that is important in maintaining a
person's independence in the community, access to employment, and social activities. Many …

Methods: We searched MEDLINE, EMBASE, PSYCinfo, CENTRAL, TRANSPORT, CINAHL,
reference lists of retrieved articles and narrative reviews, for studies on chronic cancer and …

Objective: To perform a systematic review of the present scientific literature on the treatment
with methadone or buprenorphine related to (1) traffic accident risk in epidemiological …

Objectives: This study compared the psychomotor performance and driving ability of patients
with chronic pain managed with stable regimens of opioid analgesics with that of normal …

Previous reviewers have concluded that opioids cause dose-related impairment in opioid-
naive volunteers on psychomotor skills related to driving. Data relating to opioid …

Background Many patients with chronic pain receive substandard analgesic therapy.
Incomplete or inadequate care often stems from physician fears of patient addiction and/or …

Rationale Chronic non-cancer pain (CNCP) is a major health problem. Patients are
increasingly treated with chronic opioid therapy (COT). Several laboratory studies have …

Objective It has been suggested that driving a car is relatively safe when the driver is treated
with nonsteroid anti-inflammatory drugs than when he or she is treated with opioid …

Background: Driving cessation is associated with poor health-related outcomes. People with
chronic diseases are often prescribed long-term opioid agonists that have the potential to …