Primary lateral sclerosis (PLS) is classically considered a 'pure'upper motor neuron disorder.
Motor cortex atrophy and pyramidal tract degeneration are thought to be pathognomonic of …

Background Primary lateral sclerosis is a progressive upper-motor-neuron disorder
associated with markedly longer survival than ALS. In contrast to ALS, the genetic …

Introduction Primary lateral sclerosis is a rare neurodegenerative disorder of the upper
motor neurons. Diagnostic criteria have changed considerably over the years, and the …

Background Primary lateral sclerosis (PLS) is traditionally solely associated with progressive
upper motor neuron dysfunction manifesting in limb spasticity, gait impairment, bulbar …

Background Primary lateral sclerosis (PLS) is a low incidence motor neuron disease which
carries a markedly better prognosis than amyotrophic lateral sclerosis (ALS). Despite …

Objectives This is a cross-sectional study aimed at investigating cognitive performances in
patients with primary lateral sclerosis (PLS) and using diffusion tensor (DT) magnetic …

Objective: Primary lateral sclerosis (PLS) is a rare form of motor neuron disease
characterised by UMN degeneration leading to slowly progressive spasticity. Whether it is a …

Primary lateral sclerosis (PLS) bears close resemblance to cases of amyotrophic lateral
sclerosis (ALS) presenting with spasticity, but histopathological studies have shown …

Primary lateral sclerosis (PLS) is a neurodegenerative disorder of the adult motor system.
Characterised by a slowly progressive upper motor neuron syndrome, the diagnosis is …

Primary lateral sclerosis (PLS) has been defined as a rare. Non-hereditary disease
characterized by progressive spinobulbar spasticity, related to the exclusive involvement of …