Hemodynamics and blood gases were measured before and 15 minutes after small (10
mg/70 kg) doses of intravenously administered morphine in two groups of patients having …

Experiments were performed on cats anesthetized with Dial-urethane. Respiration was
recorded plethysmographically and end-expiratory CO2 was monitored continuously …

Central haemodynamic and forearm vascular changes following administration of morphine
iv were studied in patients 24–30 h after open heart surgery. Right atrial pressure, heart rate …

The kinetics of morphine were studied during balanced anaesthesia in 10 patients
undergoing lower abdominal or body surface surgery, and compared with those obtained in …

Eighteen patients received morphine 0.2 mgkg− 1 in 9% saline im (n= 6), extradurally (n= 6),
or in a 10% dextrose solution intrathecally (n= 6) for pain relief after operation Plasma …

The ventilatory effects of morphine-6-glucuronide (M-6-G) and morphine-3-glucuronide (M-3-
G) were evaluated in awake dogs (n= 10). A fourth ventricle to cisterna magna perfusion …

The actions on the respiratory system of 0· 25, 0· 5 and 1· 0 mg kg–1morphine given
intramuscularly were studied in conscious dogs. Dogs breathed oxygen with 0, 2 and 4 per …

Background: Opioid‐induced vasodepressor responses have been reported in a variety of
species and laboratory models. The aim of this study was to ascertain the relative potencies …

The influence of renal failure on the disposition of morphine and its metabolites was studied
in nine patients with end-stage renal failure undergoing transplantation, and compared with …

Two groups of surgical patients each comprising six individuals received an intrathecal
injection of morphine 0.3 mg or meperidine 10 mg. Cerebrospinal fluid (CSF) and plasma …