Extracellular myocardial volume in patients with aortic stenosis

RJ Everett, TA Treibel, M Fukui, H Lee, M Rigolli… - Journal of the American …, 2020 - jacc.org
Background Myocardial fibrosis is a key mechanism of left ventricular decompensation in
aortic stenosis and can be quantified using cardiovascular magnetic resonance (CMR) …

Myocardial fibrosis and cardiac decompensation in aortic stenosis

CWL Chin, RJ Everett, J Kwiecinski, AT Vesey… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: Cardiac magnetic resonance (CMR) was used to investigate the extracellular
compartment and myocardial fibrosis in patients with aortic stenosis, as well as their …

Diffuse myocardial fibrosis in severe aortic stenosis: an equilibrium contrast cardiovascular magnetic resonance study

AS Flett, DM Sado, G Quarta, M Mirabel… - European Heart …, 2012 - academic.oup.com
Aims Haemodynamics alone do not fully explain symptoms and prognosis in clinically
severe aortic stenosis (AS). Myocardial disease, specifically diffuse myocardial fibrosis …

Myocardial T1 and extracellular volume fraction measurement in asymptomatic patients with aortic stenosis: reproducibility and comparison with age-matched controls

A Singh, MA Horsfield, S Bekele… - European Heart …, 2015 - academic.oup.com
Aims (i) To establish the test–retest reproducibility of myocardial T1 and extracellular volume
(ECV) fraction measurement in asymptomatic patients with moderate–severe aortic stenosis …

[HTML][HTML] Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance

MR Dweck, S Joshi, T Murigu, A Gulati… - Journal of …, 2012 - Elsevier
Background Cardiovascular magnetic resonance (CMR) is the gold standard non-invasive
method for determining left ventricular (LV) mass and volume but has not been used …

Reverse myocardial remodeling following valve replacement in patients with aortic stenosis

TA Treibel, R Kozor, R Schofield, G Benedetti… - Journal of the American …, 2018 - jacc.org
Background: Left ventricular (LV) hypertrophy, a key process in human cardiac disease,
results from cellular (hypertrophy) and extracellular matrix expansion (interstitial fibrosis) …

Imaging and impact of myocardial fibrosis in aortic stenosis

R Bing, JL Cavalcante, RJ Everett, MA Clavel… - JACC: Cardiovascular …, 2019 - jacc.org
Aortic stenosis is characterized both by progressive valve narrowing and the left ventricular
remodeling response that ensues. The only effective treatment is aortic valve replacement …

Assessment of myocardial fibrosis using multimodality imaging in severe aortic stenosis: comparison with histologic fibrosis

SJ Park, SW Cho, SM Kim, J Ahn, K Carriere… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: This study assessed diffuse myocardial fibrosis (MF) by cardiac magnetic
resonance (CMR) imaging and speckle-tracking echocardiography (STE) in patients with …

A clinical risk score of myocardial fibrosis predicts adverse outcomes in aortic stenosis

CWL Chin, D Messika-Zeitoun, ASV Shah… - European heart …, 2016 - academic.oup.com
Aims Midwall myocardial fibrosis on cardiovascular magnetic resonance (CMR) is a marker
of early ventricular decompensation and adverse outcomes in aortic stenosis (AS). We …

Progression of hypertrophy and myocardial fibrosis in aortic stenosis: a multicenter cardiac magnetic resonance study

RJ Everett, L Tastet, MA Clavel, CWL Chin… - Circulation …, 2018 - Am Heart Assoc
Background: Aortic stenosis is accompanied by progressive left ventricular hypertrophy and
fibrosis. We investigated the natural history of these processes in asymptomatic patients and …