Extracellular volume fraction for characterization of patients with heart failure and preserved ejection fraction

KP Rommel, M von Roeder, K Latuscynski… - Journal of the American …, 2016 - jacc.org
Background: Optimal patient characterization in heart failure with preserved ejection fraction
(HFpEF) is essential to tailor successful treatment strategies. Cardiac magnetic resonance …

Interstitial fibrosis, functional status, and outcomes in heart failure with preserved ejection fraction: insights from a prospective cardiac magnetic resonance imaging …

F Duca, AA Kammerlander, C Zotter-Tufaro… - Circulation …, 2016 - Am Heart Assoc
Background—Myocardial extracellular volume (ECV) accumulation is one of the key
pathophysiologic features of heart failure with preserved ejection fraction (HFpEF). Our aims …

Relationship between focal and diffuse fibrosis assessed by CMR and clinical outcomes in heart failure with preserved ejection fraction

P Kanagala, ASH Cheng, A Singh, JN Khan… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: This study sought to assess the presence and extent of focal and diffuse fibrosis
in heart failure in patients with preserved ejection fraction (HFpEF) compared to …

T1 mapping in dilated cardiomyopathy with cardiac magnetic resonance: quantification of diffuse myocardial fibrosis and comparison with endomyocardial biopsy

F aus dem Siepen, SJ Buss… - European Heart …, 2015 - academic.oup.com
Aim The aim of this study was to determine the value of extracellular volume fraction (ECV)
for the non-invasive assessment of diffuse myocardial fibrosis (MF) in different stages of …

[HTML][HTML] Associations and prognostic significance of diffuse myocardial fibrosis by cardiovascular magnetic resonance in heart failure with preserved ejection fraction

C Roy, A Slimani, C de Meester, M Amzulescu… - Journal of …, 2018 - Elsevier
Background Increased myocardial fibrosis may play a key role in heart failure with preserved
ejection fraction (HFpEF) pathophysiology. The study aim was to evaluate the presence …

Myocardial extracellular volume fraction adds prognostic information beyond myocardial replacement fibrosis

EY Yang, MG Ghosn, MA Khan… - Circulation …, 2019 - Am Heart Assoc
Background: Cardiac magnetic resonance techniques permit quantification of the
myocardial extracellular volume fraction (ECV), representing a surrogate marker of reactive …

Myocardial fibrosis quantified by extracellular volume is associated with subsequent hospitalization for heart failure, death, or both across the spectrum of ejection …

EB Schelbert, KM Piehler, KM Zareba… - Journal of the …, 2015 - Am Heart Assoc
Background Myocardial fibrosis (MF) in noninfarcted myocardium may be an interstitial
disease pathway that confers vulnerability to hospitalization for heart failure, death, or both …

[HTML][HTML] Cardiovascular magnetic resonance feature tracking for characterization of patients with heart failure with preserved ejection fraction: correlation of global …

H Ito, M Ishida, W Makino, Y Goto, Y Ichikawa… - Journal of …, 2020 - Elsevier
Background Left ventricular (LV) diastolic dysfunction is the main cause of heart failure with
preserved ejection fraction (HFpEF), and is characterized by LV stiffness and relaxation …

CMR-verified diffuse myocardial fibrosis is associated with diastolic dysfunction in HFpEF

MYM Su, LY Lin, YHE Tseng, CC Chang, CK Wu… - JACC: Cardiovascular …, 2014 - jacc.org
Objectives: The purpose of this study was to investigate diffuse myocardial fibrosis in
patients with systolic heart failure (SHF) and in patients with heart failure with preserved …

Biomarkers of diastolic dysfunction and myocardial fibrosis: application to heart failure with a preserved ejection fraction

MR Zile, CF Baicu - Journal of cardiovascular translational research, 2013 - Springer
Comprehensive diagnostic criteria, accurate prognostic indicators, and effective treatment
for patients with heart failure and a preserved ejection fraction (HFpEF) represent a critically …