Apathy and impulsivity are common and disabling consequences of frontotemporal lobar
degeneration. They cause substantial carer distress, but their aetiology remains elusive …

Highlights•Apathy and impulsivity are common consequences of frontotemporal lobar
degeneration syndromes.•Common frontostriatal loops mediate different modes of apathy …

Objective To determine the influence of apathy, impulsivity, and behavioral change on
survival in patients with frontotemporal dementia, progressive supranuclear palsy, and …

Apathy is a symptom shared among many neurological and psychiatric disorders. However,
the underlying neurocircuitry remains incompletely understood. Apathy is one of the core …

Objective: To investigate the neural basis for the behavioral symptoms of frontotemporal
lobar degeneration (FTLD) that cause the greatest caregiver distress. Background: FTLD is a …

Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disease associated with
dramatic changes in emotion. The precise nature of these changes is not fully understood; …

The syndromes caused by frontotemporal lobar degeneration have highly heterogeneous
and overlapping clinical features. There has been great progress in the refinement of clinical …

Frontotemporal lobar degeneration (FTLD) represent a constellation of disorders that may
be overlooked or misdiagnosed, despite being fairly common presenile neurodegenerative …

Background: Frontotemporal lobar degeneration (FTLD) is associated with a profound
decline in social and emotional behavior; however, current understanding regarding the …

Background Apathy is a common and significant problem in patients with dementia,
regardless of its cause. Observations about frontosubcortical circuit syndromes indicate that …