Multi-parametric spinal cord MRI as potential progression marker in amyotrophic lateral sclerosis

MM El Mendili, J Cohen-Adad, M Pelegrini-Issac… - PloS one, 2014 - journals.plos.org
Objective To evaluate multimodal MRI of the spinal cord in predicting disease progression
and one-year clinical status in amyotrophic lateral sclerosis (ALS) patients. Materials and …

[HTML][HTML] Longitudinal evaluation of cerebral and spinal cord damage in amyotrophic lateral sclerosis

M de Albuquerque, LMT Branco, TJR Rezende… - NeuroImage: Clinical, 2017 - Elsevier
Objective To evaluate MRI-based parameters as biomarkers of Amyotrophic Lateral
Sclerosis (ALS) progression. Methods Twenty-seven patients and 27 controls performed two …

Spinal cord multi‐parametric magnetic resonance imaging for survival prediction in amyotrophic lateral sclerosis

G Querin, MM El Mendili, T Lenglet… - European journal of …, 2017 - Wiley Online Library
Background and purpose Assessing survival is a critical issue in patients with amyotrophic
lateral sclerosis (ALS). Neuroimaging seems to be promising in the assessment of disease …

Spinal cord atrophy correlates with disease duration and severity in amyotrophic lateral sclerosis

LMT Branco, M De Albuquerque… - … Lateral Sclerosis and …, 2014 - Taylor & Francis
Our objective was to investigate spinal cord (SC) atrophy in amyotrophic lateral sclerosis
(ALS) patients, and to determine whether it correlates with clinical parameters. Forty-three …

Region‐specific impairment of the cervical spinal cord (SC) in amyotrophic lateral sclerosis: a preliminary study using SC templates and quantitative MRI (diffusion …

H Rasoanandrianina, AM Grapperon… - NMR in …, 2017 - Wiley Online Library
In this preliminary study, our objective was to investigate the potential of high‐resolution
anatomical imaging, diffusion tensor imaging (DTI) and conventional/inhomogeneous …

[HTML][HTML] Structural and diffusion imaging versus clinical assessment to monitor amyotrophic lateral sclerosis

A Cardenas-Blanco, J Machts, J Acosta-Cabronero… - NeuroImage: Clinical, 2016 - Elsevier
Amyotrophic lateral sclerosis is a progressive neurodegenerative disease that affects upper
and lower motor neurons. Observational and intervention studies can be tracked using …

Structural MRI correlates of amyotrophic lateral sclerosis progression

J Senda, N Atsuta, H Watanabe… - Journal of Neurology …, 2017 - jnnp.bmj.com
Purpose Amyotrophic lateral sclerosis (ALS) presents with varying degrees of brain
degeneration that can extend beyond the corticospinal tract (CST). Furthermore, the clinical …

MRI predictors of long‐term evolution in amyotrophic lateral sclerosis

F Agosta, E Pagani, M Petrolini… - European Journal of …, 2010 - Wiley Online Library
We investigated whether conventional and diffusion tensor (DT) magnetic resonance
imaging (MRI) features of the corticospinal tract (CST) contribute to the prediction of the long …

Progression of white matter degeneration in amyotrophic lateral sclerosis: a diffusion tensor imaging study

Y Zhang, N Schuff, SC Woolley… - Amyotrophic Lateral …, 2011 - Taylor & Francis
Whether longitudinal diffusion tensor MRI imaging (DTI) can capture disease progression in
patients with amyotrophic lateral sclerosis (ALS) is unclear. The primary goal of this study …

Combined MR spectroscopic imaging and diffusion tensor MRI visualizes corticospinal tract degeneration in amyotrophic lateral sclerosis

H Yin, CCT Lim, L Ma, Y Gao, Y Cai, D Li, Y Liang… - Journal of …, 2004 - Springer
Motor neuron damage and cortical spinal tract (CST) degeneration are pathological features
of amyotrophic lateral sclerosis (ALS). We combined whole-brain diffusion tensor imaging …