Human non-contrast T1 values and correlation with histology in diffuse fibrosis

S Bull, SK White, SK Piechnik, AS Flett, VM Ferreira… - Heart, 2013 - heart.bmj.com
Background Aortic stenosis (AS) leads to diffuse fibrosis in the myocardium, which is linked
to adverse outcome. Myocardial T1 values change with tissue composition. Objective To test …

Assessment of diffuse myocardial fibrosis by using MR imaging in asymptomatic patients with aortic stenosis

SP Lee, W Lee, JM Lee, EA Park, HK Kim, YJ Kim… - Radiology, 2015 - pubs.rsna.org
Purpose To assess whether native T1 mapping provides noninvasive estimation of diffuse
myocardial fibrosis and whether it correlates with subclinical myocardial dysfunction in …

Noncontrast myocardial T1 mapping by cardiac magnetic resonance predicts outcome in patients with aortic stenosis

H Lee, JB Park, YE Yoon, EA Park, HK Kim… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives: The aim of this study was to evaluate whether native T1 value of the myocardium
on cardiac magnetic resonance (CMR) could predict clinical events in patients with …

Equilibrium contrast cardiovascular magnetic resonance for the measurement of diffuse myocardial fibrosis: preliminary validation in humans

AS Flett, MP Hayward, MT Ashworth, MS Hansen… - Circulation, 2010 - Am Heart Assoc
Background—Diffuse myocardial fibrosis is a final end point in most cardiac diseases. It is
missed by the cardiovascular magnetic resonance (CMR) late gadolinium enhancement …

Assessment of myocardial fibrosis using multimodality imaging in severe aortic stenosis: comparison with histologic fibrosis

SJ Park, SW Cho, SM Kim, J Ahn, K Carriere… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: This study assessed diffuse myocardial fibrosis (MF) by cardiac magnetic
resonance (CMR) imaging and speckle-tracking echocardiography (STE) in patients with …

Optimization and comparison of myocardial T1 techniques at 3T in patients with aortic stenosis

CWL Chin, S Semple, T Malley, AC White… - European Heart …, 2014 - academic.oup.com
Aims To determine the optimal T1 mapping approach to assess myocardial fibrosis at 3T.
Methods and results T1 mapping was performed at 3T using the modified look-locker …

[HTML][HTML] Histological Validation of measurement of diffuse interstitial myocardial fibrosis by myocardial extravascular volume fraction from Modified Look-Locker …

CM de Ravenstein, C Bouzin, S Lazam, J Boulif… - Journal of …, 2015 - Elsevier
Abstract Background Gadolinium (Gd) Extracellular volume fraction (ECV) by
Cardiovascular Magnetic Resonance (CMR) has been proposed as a non-invasive method …

Diffuse myocardial fibrosis in severe aortic stenosis: an equilibrium contrast cardiovascular magnetic resonance study

AS Flett, DM Sado, G Quarta, M Mirabel… - European Heart …, 2012 - academic.oup.com
Aims Haemodynamics alone do not fully explain symptoms and prognosis in clinically
severe aortic stenosis (AS). Myocardial disease, specifically diffuse myocardial fibrosis …

Comparison of MOLLI, shMOLLLI, and SASHA in discrimination between health and disease and relationship with histologically derived collagen volume fraction

N Child, G Suna, D Dabir, ML Yap… - European Heart …, 2018 - academic.oup.com
Aims To determine the bioequivalence of several T1 mapping sequences in myocardial
characterization of diffuse myocardial fibrosis. Methods and results We performed an intra …

Imaging and impact of myocardial fibrosis in aortic stenosis

R Bing, JL Cavalcante, RJ Everett, MA Clavel… - JACC: Cardiovascular …, 2019 - jacc.org
Aortic stenosis is characterized both by progressive valve narrowing and the left ventricular
remodeling response that ensues. The only effective treatment is aortic valve replacement …