[HTML][HTML] White matter microstructure breakdown in the motor neuron disease spectrum: recent advances using diffusion magnetic resonance imaging

S Basaia, M Filippi, EG Spinelli, F Agosta - Frontiers in Neurology, 2019 - frontiersin.org
Motor neuron disease (MND) is a fatal progressive neurodegenerative disorder
characterized by the breakdown of the motor system. The clinical spectrum of MND …

Neuroanatomical patterns of cerebral white matter involvement in different motor neuron diseases as studied by diffusion tensor imaging analysis

HP Mueller, A Unrath, HJ Huppertz… - Amyotrophic Lateral …, 2012 - Taylor & Francis
This study was designed to investigate differences of white matter (WM) involvement
patterns in various motor neuron disorders (MND) by use of diffusion tensor imaging (DTI) …

Whole brain‐based analysis of regional white matter tract alterations in rare motor neuron diseases by diffusion tensor imaging

A Unrath, HP Müller, A Riecker… - Human brain …, 2010 - Wiley Online Library
Different motor neuron disorders (MNDs) are mainly defined by the clinical presentation
based on the predominance of upper or lower motor neuron impairment and the course of …

[HTML][HTML] Recent advances in using diffusion tensor imaging to study white matter alterations in Parkinson's disease: A mini review

YC Shih, WYI Tseng… - Frontiers in Aging …, 2023 - frontiersin.org
Parkinson's disease (PD) is the second most common age-related neurodegenerative
disease with cardinal motor symptoms. In addition to motor symptoms, PD is a …

Assessing white matter pathology in early-stage Parkinson disease using diffusion MRI: a systematic review

M Bergamino, EG Keeling, VR Mishra… - Frontiers in …, 2020 - frontiersin.org
Structural brain white matter (WM) changes such as axonal caliber, density, myelination, and
orientation, along with WM-dependent structural connectivity, may be impacted early in …

[HTML][HTML] Neurometabolic alterations in motor neuron disease: insights from magnetic resonance spectroscopy

F Christidi, E Karavasilis, GD Argyropoulos… - Journal of integrative …, 2022 - imrpress.com
Magnetic resonance spectroscopy (MRS) has contributed important academic insights in
motor neuron diseases (MNDs), particularly in amyotrophic lateral sclerosis (ALS). Over the …

Structural magnetic resonance imaging findings and histopathological correlations in motor neuron diseases—A systematic review and meta-analysis

C Zejlon, D Nakhostin, S Winklhofer, A Pangalu… - Frontiers in …, 2022 - frontiersin.org
Objectives The lack of systematic evidence on neuroimaging findings in motor neuron
diseases (MND) hampers the diagnostic utility of magnetic resonance imaging (MRI). Thus …

[HTML][HTML] Longitudinal diffusion tensor imaging-based assessment of tract alterations: an application to amyotrophic lateral sclerosis

D Baldaranov, A Khomenko, I Kobor… - Frontiers in human …, 2017 - frontiersin.org
Objective: The potential of magnetic resonance imaging (MRI) as a technical biomarker for
cerebral microstructural alterations in neurodegenerative diseases is under investigation. In …

Advances in the neuroimaging of motor disorders

EL Weil, MO Nakawah, JC Masdeu - Handbook of Clinical Neurology, 2023 - Elsevier
Neuroimaging is a valuable adjunct to the history and examination in the evaluation of motor
system disorders. Conventional imaging with computed tomography or magnetic resonance …

Promises and pitfalls of imaging-based biomarkers in motor neuron diseases

EL Tan, P Bede, PF Pradat - Current Opinion in Neurology, 2023 - journals.lww.com
Although we acknowledge the academic achievements of large descriptive studies, an
unmet priority of neuroimaging in MND is the development of robust diagnostic, prognostic …