One of the major challenges facing gene therapy is the development of vectors targeting
specific cell types. Restricting gene delivery to the relevant cell type leads to reduced T-cell …

While a source of great misery, lentiviruses can be modified and channeled toward the
useful purpose of developing vectors for gene transfer in gene therapy, functional genomics …

Nine different recombinant clones spanning various regions of the bovine immunodeficiency-
like virus (BIV) envelope gene open reading frame were generated. These clones span the …

An Escherichia coli recombinant fusion protein containing the major core protein of bovine
immunodeficiency-like virus (BIV) was used to immunize mice for generation of monoclonal …

The target sequences were amplified and cloned successfully. The sequencing results
showed no difference from previous reports. Antibodies against HBsAg and HCV were …

Objective To character HBV antigen expression in vitro and in vivo transduced by different
transgenic plasmids carrying infectious genome of hepatitis B virus (HBV). Methods We …

In order to quantitate the bovine immunodeficiency virus (BIV) infection in vitro, a BIV
indicator cell line (BIVL) was established by transfecting baby hamster kidney cells with …

Background New simian–human immunodeficiency chimeric viruses with an HIV-1 env
(SHIVenv) are critical for studies on HIV pathogenesis, vaccine development, and …

Mutational analyses and complementation tests were used to analyze the strategy of
packaging and of replication of human hepatitis B virus (HBV). By creating new restriction …

The hepadnaviruses (for hepatotropic DNA viruses) are a family of small enveloped DNA
animal viruses that share a common structure and liver tropism (28). The human hepatitis B …