A systematic review/meta‐analysis of prevalence and incidence rates illustrates systemic underrepresentation of individuals racialized as Asian and/or Asian …

Y Zhu, S Park, R Kolady, W Zha, Y Ma… - Alzheimer's & …, 2024 - Wiley Online Library
We investigate Alzheimer's disease and related dementia (ADRD) prevalence, incidence
rate, and risk factors in individuals racialized as Asian and/or Asian‐American and assess …

The Alzheimer's Disease Sequencing Project–Follow Up Study (ADSP‐FUS): Increasing ethnic diversity in Alzheimer's genetics research with the addition of potential …

PR Mena, BW Kunkle, KM Faber… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract Background The ADSP‐FUS is a National Institute on Aging (NIA) initiative focused
on identifying genetic risk and protective variants for late‐onset Alzheimer Disease (LOAD) …

Alzheimer's disease: insights for risk evaluation and prevention in the Chinese population and the need for a comprehensive programme in Hong Kong/China

A Yee, NBY Tsui, YN Chang, CSM Au… - Hong Kong medical …, 2018 - ira.lib.polyu.edu.hk
With the ageing of the global population, China is projected to be impacted significantly by
the rising number of patients with Alzheimer's disease (AD). A cure for AD is not yet …

Admixture mapping reveals the association between Native American ancestry at 3q13. 11 and reduced risk of Alzheimer's disease in Caribbean Hispanics

ARVR Horimoto, D Xue, TA Thornton… - Alzheimer's Research & …, 2021 - Springer
Background Genetic studies have primarily been conducted in European ancestry
populations, identifying dozens of loci associated with late-onset Alzheimer's disease (AD) …

Disparities by race and ethnicity among adults recruited for a preclinical Alzheimer disease trial

R Raman, YT Quiroz, O Langford, J Choi… - JAMA Network …, 2021 - jamanetwork.com
Importance Underrepresentation of many racial/ethnic groups in Alzheimer disease (AD)
clinical trials limits generalizability of results and hinders opportunities to examine potential …

Estimating prevalence of early Alzheimer's disease in the United States, accounting for racial and ethnic diversity

C Gillis, P Montenigro, M Nejati… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Updated estimates of the US Alzheimer's disease (AD) population, including
under‐represented populations, are needed to improve clinical trial diversity. Methods A …

What influences the willingness of Blacks and African Americans to enroll in preclinical Alzheimer's disease biomarker research? A qualitative vignette analysis

FB Ketchum, CM Erickson, NA Chin… - Journal of …, 2022 - content.iospress.com
Background: Alzheimer's disease (AD) begins with an asymptomatic “preclinical” phase, in
which abnormal biomarkers indicate risk for developing cognitive impairment. Research is …

Improving generalizability and study design of Alzheimer's disease cohort studies in the United States by including under‐represented populations

MR Mindt, O Okonkwo, MW Weiner… - Alzheimer's & …, 2023 - Wiley Online Library
The poor generalizability of clinical research data due to the enrollment of highly educated,
non‐Latinx White participants hampers the development of therapies for Alzheimer's …

A global view of the genetic basis of Alzheimer disease

C Reitz, MA Pericak-Vance, T Foroud… - Nature Reviews …, 2023 - nature.com
The risk of Alzheimer disease (AD) increases with age, family history and informative genetic
variants. Sadly, there is still no cure or means of prevention. As in other complex diseases …

Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer's disease risk

D Shigemizu, R Mitsumori, S Akiyama… - Translational …, 2021 - nature.com
Alzheimer's disease (AD) has no cure, but early detection and risk prediction could allow
earlier intervention. Genetic risk factors may differ between ethnic populations. To discover …