Perspective on the “African American participation in Alzheimer disease research: Effective strategies” workshop, 2018

A Denny, M Streitz, K Stock… - Alzheimer's & …, 2020 - Wiley Online Library
Abstract The Washington University School of Medicine Knight Alzheimer Disease Research
Center's “African American Participation in Alzheimer Disease Research: Effective …

Let's not repeat history's mistakes: two cautions to scientists on the use of race in Alzheimer's disease and Alzheimer's disease related dementias research

SD Stites, NB Coe - Journal of Alzheimer's Disease, 2023 - content.iospress.com
Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) research has
advanced gene and biomarker technologies to aid identification of individuals at risk for …

Top Alzheimer's disease risk allele frequencies differ in HABS‐HD Mexican‐versus Non‐Hispanic White Americans

M Housini, Z Zhou, J Gutierrez, S Rao… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION: Here we evaluate frequencies of the top 10 Alzheimer's disease (AD) risk
alleles for late‐onset AD in Mexican American (MA) and non‐Hispanic White (NHW) …

[引用][C] P1‐350: ALZHEIMER'S DISEASE SEQUENCING PROJECT DATA PORTAL

DM Childress, O Valladares, A Partch… - Alzheimer's & …, 2014 - Wiley Online Library
Background The Alzheimer's Disease Sequencing Project (ADSP) was announced in
February 2012 by National Institutes of Health (NIH) to sequence the genomes of a large …

Evaluating the Alzheimer's disease data landscape

C Birkenbihl, Y Salimi… - … Research & Clinical …, 2020 - Wiley Online Library
Introduction Numerous studies have collected Alzheimer's disease (AD) cohort data sets. To
achieve reproducible, robust results in data‐driven approaches, an evaluation of the present …

[HTML][HTML] Pervasive biases in proxy GWAS based on parental history of Alzheimer's disease

Y Wu, Z Sun, Q Zheng, J Miao, S Dorn, S Mukherjee… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Almost every recent Alzheimer's disease (AD) genome-wide association study (GWAS) has
performed meta-analysis to combine studies with clinical diagnosis of AD with studies that …

A survey of attitudes toward clinical trials and genetic disclosure in autosomal dominant Alzheimer's disease

JD Grill, RJ Bateman, V Buckles, A Oliver… - Alzheimer's research & …, 2015 - Springer
Introduction Because of its genetic underpinnings and consistent age of onset within
families, autosomal dominant Alzheimer's disease (ADAD) provides a unique opportunity to …

[HTML][HTML] Overcoming Racial/Ethnic Disparities in Alzheimer Disease and Related Dementias: Time for a Closer Look

KC Ferdinand - JACC: Advances, 2024 - jacc.org
In 1906, Alois Alzheimer, a clinical psychiatrist and neuroanatomist, described “a peculiar
severe disease process of the cerebral cortex” in a 50-year-old woman with paranoia …

Risk of Alzheimer's disease and related dementia by sex and race/ethnicity: The Multiethnic Cohort Study

U Lim, S Wang, SY Park, D Bogumil… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Data are limited for comparison of sex‐and race/ethnicity‐specific risks of
Alzheimer's disease and related dementia (ADRD). Methods In the population‐based …

Targeted sequencing of Alzheimer disease genes in African Americans implicates novel risk variants

MW Logue, D Lancour, J Farrell, I Simkina… - Frontiers in …, 2018 - frontiersin.org
The genetic architecture of late-onset Alzheimer disease (AD) in African Americans (AAs)
differs from that in persons of European ancestry. In addition to APOE, genome-wide …