Genetic associations between modifiable risk factors and Alzheimer disease

J Luo, JQ Thomassen, C Bellenguez… - JAMA network …, 2023 - jamanetwork.com
Importance An estimated 40% of dementia is potentially preventable by modifying 12 risk
factors throughout the life course. However, robust evidence for most of these risk factors is …

Racial and Ethnic Differences in the Population-Attributable Fractions of Alzheimer Disease and Related Dementias

SY Park, VW Setiawan, EM Crimmins, LR White… - Neurology, 2024 - AAN Enterprises
Background and Objectives Previous studies estimated that modifiable risk factors explain
up to 40% of the dementia cases in the United States and that this population-attributable …

[HTML][HTML] Culture, ethnicity, and level of education in Alzheimer's disease

M Rosselli, IV Uribe, E Ahne, L Shihadeh - Neurotherapeutics, 2023 - Elsevier
Alzheimer's disease (AD) is the most frequent cause of dementia, where the abnormal
accumulation of beta-amyloid (Aβ) and tau lead to neurodegeneration as well as loss of …

NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS): 2022 Update

H Issen, AB Kuzma, O Valladares… - Alzheimer's & …, 2022 - Wiley Online Library
Background NIAGADS is a national genomics data repository that facilitates access of
genotypic and sequencing data to qualified investigators for the study of the genetics of …

Call for Collecting and Reporting Disaggregated Data for Centering Racial Inclusion and Equity in the US and Globally: Examining Multimorbidity and Risk for …

PP Zanwar, R Taylor, PC Heyn - Alzheimer's & Dementia, 2023 - Wiley Online Library
Abstract Background Asian American subgroups are underrepresented in Alzheimers
Disease and Related Dementias (ADRD) research in the US and globally. Method Our …

Risk factors associated with Alzheimer disease and related dementias by sex and race and ethnicity in the US

RA Nianogo, A Rosenwohl-Mack, K Yaffe… - JAMA …, 2022 - jamanetwork.com
Importance Previous estimates suggested that 1 in 3 cases of Alzheimer disease and related
dementia (ADRDs) in the US are associated with modifiable risk factors, the most prominent …

Barriers and facilitators of African American participation in Alzheimer disease biomarker research

MM Williams, DP Scharff, KJ Mathews… - Alzheimer Disease & …, 2010 - journals.lww.com
African Americans experience a greater risk of Alzheimer disease (AD), but are
underrepresented in AD research. Our study examined barriers and facilitators of AD …

[引用][C] P4‐623: LESSONS FROM A RESEARCH COLLABORATION WITH THE ONEIDA NATION OF WISCONSIN

C Trojanczyk, M Zuelsdorff, M Summers… - Alzheimer's & …, 2019 - Wiley Online Library
Background As Alzheimer's disease and related dementias prevalence (ADRD) increases it
will disproportionately burden racial and ethnic minority communities. Recent population …

[HTML][HTML] Alzheimer's disease variant portal: a Catalog of genetic findings for Alzheimer's disease

PP Kuksa, CL Liu, W Fu, L Qu, Y Zhao… - Journal of …, 2022 - content.iospress.com
Background: Recent Alzheimer's disease (AD) genetics findings from genome-wide
association studies (GWAS) span progressively larger and more diverse populations and …

Examining the Interactive Effect of Cardiovascular Risk Factors and APOE Genotype on Population Health Disparities in dementia risk

SJ Andrews, AE Renton, B Fulton‐Howard… - Alzheimer's & …, 2023 - Wiley Online Library
Background There is a need to better understand the role of modifiable risk factors in the
development of racial/ethnic health disparities in Alzheimer's disease (AD). In particular …