Buprenorphine kinetics was determined in surgical patients using radioimmunoassay.
Buprenorphine was measured in the plasma of 24 patients who had received 0.3 mg …

1 A 10 h study of plasma drug concentrations of the opiate buprenorphine after use was
designed because a previous 3 h study had shown that peak plasma drug concentrations in …

The plasma concentrations and clinical effects of a single iv dose of buprenorphine 0.3 or
0.6 mg were studied in patients recovering from surgery. Analgesic and hormonal effects …

1 Buprenorphine is a long‐acting opiate analgesic. This study was designed to investigate
the pharmacokinetics of this drug when given by the sublingual route to ten postoperative …

The pharmacologie profile of sublingual and subcutaneous buprenorphine, a partial opioid
agonist, indicates it may be useful as a maintenance drug in the treatment of opioid …

Buprenorphine is a semi-synthetic opioid derived from thebaine, a naturally occurring
alkaloid of the opium poppy, Papaver somniferum. The pharmacology of buprenorphine is …

Synopsis: Buprenorphine 1, a derivative of the morphine alkaloid thebaine, is a strong
analgesic with marked narcotic antagonist activity. In studies in relatively small groups of …

Background Prescribed sublingual (SL) buprenorphine is sometimes diverted for
intravenous (IV) abuse, but no human pharmacokinetic data are available following high …

Objective The purpose of this study was to characterize the acute effects of buprenorphine,
an opioid partial (μ‐agonist, across a wide range of doses in comparison to methadone …

Buprenorphine, a partial opiate‐receptor agonist with potent analgesic properties, was given
to 7548 patients in the immediate postoperative period. Ninety per cent of patients had good …