Pharmacokinetics of the combination tablet of buprenorphine and naloxone
CN Chiang, RL Hawks - Drug and alcohol dependence, 2003 - Elsevier
The sublingual combination tablet formulation of buprenorphine and naloxone at a fixed
dose ratio of 4: 1 has been shown to be as effective as the tablet formulation containing only …
dose ratio of 4: 1 has been shown to be as effective as the tablet formulation containing only …
Buprenorphine pharmacokinetics: relative bioavailability of sublingual tablet and liquid formulations
RP Nath, RA Upton, ET Everhart… - The Journal of …, 1999 - Wiley Online Library
Buprenorphine is an effective new treatment for opiate dependence. This study compared
the bioavailability of buprenorphine from a tablet to that from a reference solution. Six men …
the bioavailability of buprenorphine from a tablet to that from a reference solution. Six men …
The radioimmunoassay of buprenorphine
AJ Bartlett, JG Lloyd-Jones, MJ Rance… - European Journal of …, 1980 - Springer
Antisera to buprenorphine were obtained in rabbits immunised with 3-0-
carboxymethylbuprenorphine and N-hemisuccinyl-norbuprenorphine conjugated to obvine …
carboxymethylbuprenorphine and N-hemisuccinyl-norbuprenorphine conjugated to obvine …
Determination of buprenorphine by high-performance liquid chromatography with fluorescence detection: application to human and rabbit pharmacokinetic studies
ST Ho, JJ Wang, W Ho, OYP Hu - Journal of Chromatography B …, 1991 - Elsevier
A rapid, sensitive, precise and accurate high-performance liquid chromatographic assay
with fluorescence detection was developed for the determination of buprenorphine in …
with fluorescence detection was developed for the determination of buprenorphine in …
Characterization of the pharmacokinetics of buprenorphine and norbuprenorphine in rats after intravenous bolus administration of buprenorphine
S Gopal, TB Tzeng, A Cowan - European journal of pharmaceutical …, 2002 - Elsevier
The purpose of this project was to characterize the dose-dependent pharmacokinetics of
buprenorphine (BN) and norbuprenorphine (NBN), the primary metabolite, after intravenous …
buprenorphine (BN) and norbuprenorphine (NBN), the primary metabolite, after intravenous …
[引用][C] Absorption, distribution, metabolism, and excretion of buprenorphine in animals and humans
DS Walter, CE Inturrisi - Buprenorphine: combatting drug abuse with a unique …, 1995
Pharmacokinetics and subjective effects of sublingual buprenorphine, alone or in combination with naloxone: lack of dose proportionality
DS Harris, JE Mendelson, ET Lin, RA Upton… - Clinical …, 2004 - Springer
Objective: Buprenorphine and buprenorphine/naloxone combinations are effective
pharmacotherapies for opioid dependence, but doses are considerably greater than …
pharmacotherapies for opioid dependence, but doses are considerably greater than …
Comparison of buprenorphine, pethidine and pentazocine for the relief of pain after operation
BC Hovell - BJA: British Journal of Anaesthesia, 1977 - academic.oup.com
The analgesic effects of buprenorphine 2 μg. kg− 1, 4 μg. kg− 1 and 8μg. kg− 1 were
compared with those of pethidine 1 mg. kg− 1 and pentazocine 0.6 mg. kg− 1 in 172 patients …
compared with those of pethidine 1 mg. kg− 1 and pentazocine 0.6 mg. kg− 1 in 172 patients …
Clinical efficacy of buprenorphine: comparisons to methadone and placebo
W Ling, DR Wesson - Drug and Alcohol Dependence, 2003 - Elsevier
Buprenorphine has been studied extensively since 1978 when it was initially proposed as
an alternative to methadone for treatment of opioid dependence. Early work by Jasinski …
an alternative to methadone for treatment of opioid dependence. Early work by Jasinski …
Buprenorphine: new pharmacological aspects.
A Cowan - International journal of clinical practice. Supplement, 2003 - europepmc.org
Buprenorphine is an opioid analgesic, derived from thebaine. Buprenorphine was initially
classified as a" mixed agonist-antagonist analgesic" or a narcotic antagonist analgesic. The …
classified as a" mixed agonist-antagonist analgesic" or a narcotic antagonist analgesic. The …