Morphinan derivatives with an oxabicyclo [3.2. 1] octane structure as dual agonists toward δ and κ opioid receptors

Y Uenohara, S Tsumura, S Hirayama, E Higashi… - Bioorganic & Medicinal …, 2022 - Elsevier
The κ opioid receptor (KOR) is one of the promising targets to develop analgesics lacking
morphine like side effects. To seek a novel KOR agonist we designed 6-amide derivatives …

Morphinan derivatives with an oxabicyclo [3.2. 1] octane structure as dual agonists toward δ and κ opioid receptors

Y Uenohara, S Tsumura, S Hirayama… - Bioorganic & …, 2022 - pubmed.ncbi.nlm.nih.gov
The κ opioid receptor (KOR) is one of the promising targets to develop analgesics lacking
morphine like side effects. To seek a novel KOR agonist we designed 6-amide derivatives …

Morphinan derivatives with an oxabicyclo [3.2. 1] octane structure as dual agonists toward δ and κ opioid receptors.

Y Uenohara, S Tsumura, S Hirayama… - Bioorganic & …, 2021 - europepmc.org
The κ opioid receptor (KOR) is one of the promising targets to develop analgesics lacking
morphine like side effects. To seek a novel KOR agonist we designed 6-amide derivatives …