A case series of concomitant treatment of perhexiline with amiodarone
H Gilutz, MP Frenneaux… - Therapeutic drug …, 2012 - journals.lww.com
… 26 patients received this concomitant treatment without any … that concomitant treatment with
perhexiline and amiodarone may be … of plasma perhexiline concentrations to guide therapy. …
perhexiline and amiodarone may be … of plasma perhexiline concentrations to guide therapy. …
Can perhexiline be utilized without long-term toxicity? A clinical practice audit
… with potentially interacting drugs (such as amiodarone, 25 … ) were not contraindications to
perhexiline therapy at entry. … details regarding concomitant CYP2D6 inhibitor therapy, this study …
perhexiline therapy at entry. … details regarding concomitant CYP2D6 inhibitor therapy, this study …
Perhexiline and hypertrophic cardiomyopathy: a new horizon for metabolic modulation
JD Horowitz, YY Chirkov - Circulation, 2010 - Am Heart Assoc
… increased significantly by perhexiline therapy, with concomitant and marked amelioration …
case for the development of agents with less potential toxicity than amiodarone and perhexiline…
case for the development of agents with less potential toxicity than amiodarone and perhexiline…
Perhexiline improves symptomatic status in elderly patients with severe aortic stenosis
SA Unger, MA Robinson… - Australian and New …, 1997 - Wiley Online Library
… report here our initial experience with perhexiline treatment … in this group of patients over
the first three months of therapy. … evidence of concomitant coronary artery disease. In addition, …
the first three months of therapy. … evidence of concomitant coronary artery disease. In addition, …
Dronedarone, amiodarone and other antiarrhythmic drugs, and acute liver injuries: a case-referent study
L Grimaldi-Bensouda, H Wedemeyer, J Wiegand… - International Journal of …, 2018 - Elsevier
… Exposure to class III antiarrhythmic drugs was 4.0% in cases and 1.5% in controls, aOR =
3.6 (95% CI: 1.6–8.4). Associations with exposure to dronedarone and amiodarone were …
3.6 (95% CI: 1.6–8.4). Associations with exposure to dronedarone and amiodarone were …
Randomized controlled trial of perhexiline on regression of left ventricular hypertrophy in patients with symptomatic hypertrophic cardiomyopathy (RESOLVE-HCM trial …
R Ananthakrishna, SL Lee, J Foote, BC Sallustio… - American Heart …, 2021 - Elsevier
… • Current treatment with perhexiline or previous adverse reaction to perhexiline at therapeutic
… of recurrent hypoglycemia• Concomitant use of amiodarone, ranolazine or trimetazidine• …
… of recurrent hypoglycemia• Concomitant use of amiodarone, ranolazine or trimetazidine• …
Systematic review of the efficacy and safety of perhexiline in the treatment of ischemic heart disease
SM Killalea, H Krum - American Journal of Cardiovascular Drugs, 2001 - Springer
… documented with amiodarone.[61] … concomitant plasma perhexiline concentrations ranging
between 720 and 2680 μg/L. Subsequently, another group of 22 similar patients were treated …
between 720 and 2680 μg/L. Subsequently, another group of 22 similar patients were treated …
Improvement in cardiac energetics by perhexiline in heart failure due to dilated cardiomyopathy
RM Beadle, LK Williams, M Kuehl, S Bowater… - JACC: Heart Failure, 2015 - jacc.org
… Each JACC Patient Care Pathway is an immersive, multimedia case report depicting the …
than twice the upper limit of normal; concomitant use of amiodarone, quinidine, haloperidol, or …
than twice the upper limit of normal; concomitant use of amiodarone, quinidine, haloperidol, or …
[PDF][PDF] A Phase 2, Multi-Center, Open-Label, Ascending Dose Study on the Efficacy, Safety and Tolerability of Perhexiline in Patients with Hypertrophic …
US IND - classic.clinicaltrials.gov
… Any concomitant disease, condition, or treatment that could interfere with the conduct of the
study, or that would, in the opinion of the investigator or sponsor, pose an unacceptable risk …
study, or that would, in the opinion of the investigator or sponsor, pose an unacceptable risk …
Drugs that affect cardiac metabolism: focus on perhexiline
CR Chong, B Sallustio, JD Horowitz - Cardiovascular drugs and therapy, 2016 - Springer
… for such therapies (for example because of concomitant severe systolic heart failure) and
by the … of the anti-ischaemic effects of perhexiline and amiodarone. However, excessive or …
by the … of the anti-ischaemic effects of perhexiline and amiodarone. However, excessive or …