… use of rating scales for evaluating LID in MPTP-lesioned primate models of PD, with a focus
on macaques, and present specifics on the Non-Human Primate Dyskinesia Rating Scale. © …

… Behavioral rating scales for dyskinesia in the non-human primate are … reporting a new global
non-human primate dyskinesia rating … could be used to detect dyskinesia, further analysis is …

… dyskinesia rating scales. Hence, for the QDS and the DRS … analysis to compare the slopes
between the two scales. In both … presented a standardized method for quantifying dyskinesia …

… can be readily distinguished and quantified with specific rating scales. More recently, … 1.1
Introduction … used to asses PD patients, such as the Unified Parkinson’s disease rating scale (…

… This model has also been valuable in the study of dyskinesia, since the … severity of intoxication
in non-human primates and the putative benefits … of these results can be open to criticism. …

… in PD patients or non-human primates when repeatedly exposed to l-… dopamine depletion
were included in the study analysis. … This was initially presented as an independent parameter …

… Non-human primate (NHP) models of Parkinson disease show many similarities … dyskinesias
appear in most patients after chronic treatment and may become disabling. Dyskinesias are …

… To evaluate the severity of motor symptoms, different scales have been developed, eg,
eight scales in the macaque (Imbert et al. 2000). These scales include different behavioral …

… rating scales have been developed to measure the severity of extra-pyramidal symptoms in
non-human primates … of 0.5 mg/kg until they presented a stable extra-pyramidal syndrome (8 …

… severity over time in the non-human primate models. Although … dyskinetic features but less
rotation behavior are presented in … behavioral assessment methods and rating scales need to …