Nonhuman primate models of Parkinson's disease

ME Emborg - ILAR journal, 2007 - academic.oup.com
… This article provides a critical review of available PD monkey models, … The treated animals
presented a significant unilateral TH-… dyskinesias associated with chronic L-dopa treatment. …

Comparison of eight clinical rating scales used for the assessment of MPTP-induced parkinsonism in the Macaque monkey

C Imbert, E Bezard, S Guitraud, T Boraud… - Journal of neuroscience …, 2000 - Elsevier
… This model has also been valuable in the study of dyskinesia, since the … severity of intoxication
in non-human primates and the putative benefits … of these results can be open to criticism. …

Behavioural impact of a double dopaminergic and serotonergic lesion in the non-human primate

M Beaudoin-Gobert, J Epinat, E Metereau, S Duperrier… - Brain, 2015 - academic.oup.com
… time a monkey model of Parkinson’s disease presenting a double … However, from post-mortem
analysis, we found a drastic … l-DOPA-induced dyskinesias in non-human primates is given …

[HTML][HTML] Transient dystonia correlates with parkinsonism after 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine in non-human primates

SA Norris, L Tian, EL Williams, JS Perlmutter - Dystonia, 2023 - frontierspartnerships.org
… treatment status rated each video clip, which was presented in a … Prior to data analysis, we
conservatively defined the … ) since the scores on these two rating scales clearly diverged as …

Modeling dyskinesia in animal models of Parkinson disease

N Morin, VA Jourdain, T Di Paolo - Experimental neurology, 2014 - Elsevier
… This article reviews rodent and non-human primate models of … rating scales used for the
motor behavioral evaluation and for detecting dyskinesia in mice are based on the rating scale

Animal behavioral assessments in current research of Parkinson's disease

T Asakawa, H Fang, K Sugiyama, T Nozaki… - … Biobehavioral Reviews, 2016 - Elsevier
… This article systematically reviews the behavioral assessments, for both motor and non-motor
symptoms, in various animal models involved in current … Parkinson’s disease rating scale

How reliable is the behavioural evaluation of dyskinesia in animal models of Parkinson's disease?

AR Carta, A Pinna, M Morelli - Behavioural pharmacology, 2006 - journals.lww.com
assessment of parkinsonian motor deficits, rating scales are used to assess the severity of
dyskinetic movements in non-human primates … and non-human primates rendered dyskinetic

Dopamine and serotonin modulation of motor and non-motor functions of the non-human primate striato-pallidal circuits in normal and pathological states

V Sgambato-Faure, L Tremblay - Journal of Neural Transmission, 2018 - Springer
… ), presentingfound that our l-DOPA treated recovered monkeys (ie MPTP-monkeys that no
longer express motor symptoms as a function of time after MPTP) did not develop dyskinesias

Models of hyperkinetic disorders in primates

E Bezard - Journal of Neuroscience Methods, 2020 - Elsevier
… in non-human primates. These disabling conditions include notably L-dopa-induced dyskinesia
in Parkinson’s disease, tardive dyskinesia… other conditions presented in this short review, …

Research advances on L-DOPA-induced dyskinesia: from animal models to human disease

X Chen, Y Wang, H Wu, C Cheng, W Le - Neurological Sciences, 2020 - Springer
… such rating scales by presenting specifics on the Non-Humannon-human primate dyskinesia
rating method, using a video-based scoring system, termed Quantitative Dyskinesia Scale (…