New targeted treatments in lung cancer—overview of clinical trials

S Korfee, T Gauler, R Hepp, C Pöttgen, W Eberhardt - Lung Cancer, 2004 - Elsevier
… In non-smallcell lung cancer a phase-II trial has tested the combination of chemotherapy
and celecoxib in advanced … TRIBUTE – A phase III trial of erlotinib (OSI-774) combined with …

… of Fei-Liu-Ping ointment in combination with celecoxib via cyclooxygenase-2-mediated lung metastatic inflammatory microenvironment in Lewis lung carcinoma …

R Liu, H Zheng, W Li, Q Guo, S He, Y Hirasaki… - Journal of translational …, 2015 - Springer
… Pemetrexed and Erlotinib are widely used as maintenance therapy for advanced non-small
cell lung cancer [7, 8]; … To the best of our knowledge, no previous literature has reported the …

[HTML][HTML] Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model with heightened airway HGF

LP Stabile, ME Rothstein, CT Gubish… - Journal of Thoracic …, 2014 - Elsevier
… is often dysregulated in nonsmall-cell lung cancer (NSCLC). … Celecoxib dose was based
on our prior observations in lung … by combining celecoxib with the EGFR inhibitor erlotinib in …

Celecoxib and mucosal protection: translation from an animal model to a phase I clinical trial of celecoxib, irinotecan, and 5-fluorouracil

MM Javle, S Cao, FA Durrani, L Pendyala… - Clinical cancer …, 2007 - AACR
nonsmall cell lung cancer cell lines (13). … study investigated the optimal biological dose
of celecoxib and reported that 600 mg bid was the preferred dose in combination with erlotinib (…

Targeted therapies in non-small cell lung cancer: proven concepts and unfulfilled promises.

J Auberger, J Loeffler-Ragg, W Wurzer… - Current cancer drug …, 2006 - ingentaconnect.com
… , a phase I/II trial combining bevacizumab with erlotinib in … combined Celecoxib with
Gefitinib in 11 patients with stage IV … : state of the art and development of new biologic agents. …

The role of celecoxib as a COX-2 inhibitor increasing the radiosensitivity of tumor tissue

Y Jalalabadi, A Shirazi… - British Journal of …, 2015 - stm.e4journal.com
… along with Erlotinib in advanced lung cancer was 600mg to be taken twice … Combining
sorafenib with celecoxib synergistically inhibits tumor growth of non-small cell lung cancer cells in …

Targeting non-small cell lung cancer with epidermal growth factor tyrosine kinase inhibitors: where do we stand, where do we go

JD Patel, B Pasche, A Argiris - Critical reviews in oncology/hematology, 2004 - Elsevier
celecoxib, a selective cyclooxygenase 2 inhibitor with antiangiogenic activity is being tested
in combination with erlotinib in a phase II study … of the biologically optimal dose. Should we …

[PDF][PDF] … COX-2 INHIBITOR, ALONE AND IN COMBINATION WITH DOCETAXEL IN HUMAN NON-SMALL CELL LUNG CARCINOMA XENOGRAFTS (Abstract# 5663)

TL Lawhon, SL Zaknoen, AJ Wong, KR Meshaw… - 2008 - Citeseer
… A phase I trial to determine the optimal biological dose of celecoxib when combined with
erlotinib in advanced non-small cell lung cancer. Clin …

Treatment of non-small cell lung cancer

R Pirker, HH Hansen - Lung Cancer Therapy Annual 6, 2008 - taylorfrancis.com
… and biologic properties of individual lung cancers which has … alone and another trial in which
erlotinib is given as maintenance … ) trial is a prospective phase II feasibility study combining

Molecular Targeted Agents in NonSmall-Cell Lung Cancer

AB Sandler - Clinical Lung Cancer, 2003 - Elsevier
… of docetaxel and the specific COX-2 inhibitor celecoxib. … -agent and combination therapy
in nonsmall cell lung cancer. … erlotinib in patients with recurrent non-small cell lung cancer (…