Allergen1 regulates polysaccharide structure in Cryptococcus neoformans

N Jain, RJB Cordero, A Casadevall… - Molecular …, 2013 - Wiley Online Library
… a role of ALL1 in regulating conformational aspects of PS structure and iron homeostasis.
These … and suggest that structural changes and polymer length are epigenetically regulated. …

Loss of Allergen 1 Confers a Hypervirulent Phenotype That Resembles Mucoid Switch Variants of Cryptococcus neoformans

N Jain, L Li, YP Hsueh, A Guerrero… - Infection and …, 2009 - Am Soc Microbiol
… By microarray and real-time PCR analyses, the allergen 1 … , all1Δ cells produced a larger
polysaccharide capsule than cells of … at 37C in SD identified differentially regulated genes that …

ALL2, a Homologue of ALL1, Has a Distinct Role in Regulating pH Homeostasis in the Pathogen Cryptococcus neoformans

N Jain, T Bouklas, A Gupta, AK Varshney… - Infection and …, 2016 - Am Soc Microbiol
… pathogen that has a polysaccharide capsule and causes life-… of allergen 1 (ALL1) results
in the secretion of a shorter, more viscous exopolysaccharide with less branching and structural

[图书][B] Physical and structural studies of Cryptococcus neoformans polysaccharide capsule

RJBC Gonzalez - 2012 - search.proquest.com
… PS structure was found to be influenced by Allergen 1 (ALL 1), a gene that is down-regulated
in a hypervirulent phenotypic switch variant of C. neoformans. ALL1 null mutants mimic this …

Physical and structural studies of Cryptococcus neoformans polysaccharide capsule

RJB Cordero Gonzalez - 2012 - repository.yu.edu
… The polysaccharide (PS) capsule of Cryptococcus neoformans … PS structure was found to
be influenced by Allergen 1 (ALL1)… -regulated in a hypervirulent phenotypic switch variant of C. …

[HTML][HTML] A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals

EE McClelland, UA Ramagopal, J Rivera, J Cox… - PLoS …, 2016 - journals.plos.org
… and structure of the capsular polysaccharide was … controls the trajectory but not host-specific
adaptation during virulence evolution of the pathogenic fungus Cryptococcus neoformans. …

ALL2, a homologue of ALL1, has a distinct role in regulating pH homeostasis in the pathogen Cryptococcus neoformans.

NJ Neena Jain, T Bouklas, AG Anjali Gupta… - 2016 - cabidigitallibrary.org
… pathogen that has a polysaccharide capsule and causes life-… of allergen 1 (ALL1) results
in the secretion of a shorter, more viscous exopolysaccharide with less branching and structural

[HTML][HTML] … novel specificity protein 1 (SP1)-like gene regulating protein kinase C-1 (Pkc1)-dependent cell wall integrity and virulence factors in Cryptococcus neoformans

A Adler, YD Park, P Larsen, V Nagarajan… - Journal of Biological …, 2011 - ASBMB
… The basidiomycete fungus Cryptococcus neoformans is a leading cause of AIDS-related
death worldwide and utilizes the calcineurin and protein kinase C-1 (Pkc1) signaling pathways …

[HTML][HTML] Genome-Wide Transcription Study of Cryptococcus neoformans H99 Clinical Strain versus Environmental Strains

E Movahed, K Munusamy, GMY Tan, CY Looi, ST Tay… - PLoS …, 2015 - journals.plos.org
… sugar transport regulators are essential for the production of capsular polysaccharide
antigens [34]. In fact, top in the list of the up-regulated genes in the H99 comprised SNF3, a gene …

Aging as an emergent factor that contributes to phenotypic variation in Cryptococcus neoformans

T Bouklas, BC Fries - Fungal Genetics and Biology, 2015 - Elsevier
… In contrast, epigenetically-regulated changes of the polysaccharide capsule that occur in the
setting of phenotypic switching affect a smaller proportion of the fungal population. However…