… III antiarrhythmic drugs including amiodarone inhibit the Na+-… sence and presence of 100
µM quinidine are shown in Fig. 3. … KNa channels may be activated during digitalis toxicity and …

… to use antidotal therapy with digoxinspecific Fab fragments (… digoxin disposition and its
pharmacological and toxic effects. Additionally, the treatment of acute digoxin toxicity in children is …

… include digoxin with quinidine, rifampicin or verapamil; and … Digoxin is not extensively
metabolized but it is transported by … like quinidine, verapamil and amiodarone, leading to digoxin …

… cizine and amiodarone, can be positioned … Quinidine potentiates the effect of anticholinergics,
warfarin, and phenothiazines. Increased digoxin levels routinely occur when quinidine is …

… Digoxin is widely used for ventricular rate control in … quinidine, verapamil or amiodarone
does not require dose reduction. Use with caution when co-administered with P-gp inducers Not …

… or diltiazem plus β-blockers, excess digitalis, or amiodarone), or on … of digitalis toxicity,
rapid IV administration of verapamil is … Verapamil and quinidine may interact to cause excess …

… of digitalis and adenosine are discussed later in this chapter. … is an amiodarone analog without
iodine in its structure; it is … in overdose, it can cause “quinidine-like” effects similar to those …

… Digoxin is not bound by adipose tissue, so the dose should be based on lean body mass .31
Amiodarone may affect digoxin’… by their direct effects on the kidney.33,34 Quinidine inhibits …

… He developed an episode of VT storm requiring 20 implantable cardioverter-defibrillator (ICD)
shocks in the context of also being quinidine and metronizadole with a digoxin level of 0.6 …

… adverse effects of positive inotropic drugs, such as digoxin … The interaction of digoxin with
quinine has only occasionally … Amiodarone also increased annexin binding after hypertonic …