Pharmacologic and therapeutic considerations in hypertension therapy with calcium channel blockers: focus on verapamil

DA Sica, LM Prisant - The Journal of Clinical Hypertension, 2007 - Wiley Online Library
… or diltiazem plus β-blockers, excess digitalis, or amiodarone), or on … of digitalis toxicity,
rapid IV administration of verapamil isVerapamil and quinidine may interact to cause excess …

[HTML][HTML] The Significance of drug—Drug and drug—Food interactions of oral anticoagulation

P Vranckx, M Valgimigli… - … & electrophysiology review, 2018 - ncbi.nlm.nih.gov
Digoxin is widely used for ventricular rate control in … quinidine, verapamil or amiodarone
does not require dose reduction. Use with caution when co-administered with P-gp inducers Not

Drug therapy and drug interactions

GA Davis, MHH Chandler - Oral and Maxillofacial Surgery Clinics of North …, 1996 - Elsevier
Digoxin toxicity can be increased when drugs such as amiodarone, quinidine, or verapamil
are used … The cardiovascular effects of digoxin are accentuated in patients whose serum …

[PDF][PDF] Drug interactions-mechanisms and clinical implications

HM Lal, U Lal - Medicine update, 2008 - Citeseer
… include digoxin with quinidine, rifampicin or verapamil; and … Digoxin is not extensively
metabolized but it is transported by … like quinidine, verapamil and amiodarone, leading to digoxin

Antiarrhythmic drug development: historical review and future perspective

MK Pugsley - Drug development research, 2002 - Wiley Online Library
… It was observed that the action of quinidine on Vmax was … effectiveness of sotalol and
amiodarone in the clinical setting, … adenosine and the digitalis glycosides are not classified. Most …

Some recent concepts concerning the mechanisms of action of antiarrhythmic drugs

MR Rosen, W Spinelli - Pacing and Clinical Electrophysiology, 1988 - Wiley Online Library
… poisoned (eg, digitalis toxicity) there will be interference with … For example, amiodarone,
originally thought to be a … Quinidine has higher affinity for the open channel state, while prooain…

Antiarrhythmic Drug Management

HH Hsia - Critical Care Study Guide: Text and Review, 2002 - Springer
… has effects of both class II and III, and amiodaroneeffects preclude long-term quinidine
therapy in up to 30% of patients. Significant drug interactions with digoxin, amiodarone, verapamil

Positive inotropic drugs and drugs used in dysrhythmias

JK Aronson - Side Effects of Drugs Annual, 2010 - Elsevier
… adverse effects of positive inotropic drugs, such as digoxin … The interaction of digoxin with
quinine has only occasionally … Amiodarone also increased annexin binding after hypertonic …

[PDF][PDF] Antiarrhythmic drugs and strategies

S Nattel, BJ Gersh, LH Opie - Drugs for the heart. Saunders …, 2013 - jvsmedicscorner.com
Amiodarone may increase quinidine and procainamide … to digitalis toxic effects (not
arrhythmias because amiodarone … discomfort that does not occur with verapamil or diltiazem. …

Positive inotropic drugs and drugs used in dysrhythmias

JK Aronson - Side Effects of Drugs Annual: A Worldwide Yearly …, 2005 - books.google.com
… of intravenous digoxin were not affected by clarithromycin. … patient who had taken quinidine
for more than 1 year). There … received amiodarone alone or in association with digoxin as …