… comparing antipsychotic monotherapy versus two antipsychotics … antipsychotic augmentation
with antipsychotic switch instead of continuation of the original antipsychotic monotherapy. …

… continued antipsychotic monotherapy in schizophrenia. Co‐primary outcomes were total …
and study‐defined response. Antipsychotic augmentation was superior to monotherapy …

… .17,25,26 However, all the studies discussed widely to date involved antipsychotic augmentation
strategies of chronically ill patients refractory to clozapine.30–33 By contrast, positive …

… during the acute phase treatment of mania were included in the present study. … meta-analyses:
MS plus AP combination or augmentation therapy was compared with MS monotherapy …

… symptoms of schizophrenia compared with antipsychotic monotherapy. Although the meta-…
For total symptom reductions, 32 strategies that augmented any antipsychotic drug and 5 …

… antipsychotic monotherapy is scarce. In this meta-analysis, 2 studies reported antipsychotic
… ; Constantine et al., 2015) and 1 study administered clozapine to all patients (Repo-Tiihonen …

… and MS therapy and AUG therapy and AP monotherapy, respectively) were included in this
study. In all studies included in this review, the response to manic symptoms was defined as …

… antipsychotic monotherapy with antipsychotic co-treatment in ≥20 adults with schizophrenia
reporting meta-… and (ii) antipsychotic augmentation (defined as the addition of a second …

… on antipsychotic augmentation … study provides the first comprehensive literature review of
pharmacological and non-pharmacological augmentation in clozapine-refractory schizophrenia…

… clozapine monotherapy. … Meta‐regression of the effect of length of treatment on effect size
showed no relationship (P = 0.254). The risk of discontinuing antipsychotic augmentation was …