Automated assessment of Ki67 in breast cancer: the utility of digital image analysis using virtual triple staining and whole slide imaging

AI Hida, D Omanovic, L Pedersen, Y Oshiro… - …, 2020 - Wiley Online Library
… an automated and reliable Ki-67 assessment approach for … Automated processes would be
better to achieve a standardised … Here, we aimed to develop an automated Ki-67 assessment

[HTML][HTML] Development and evaluation of a virtual microscopy application for automated assessment of Ki-67 expression in breast cancer

J Konsti, M Lundin, H Joensuu, T Lehtimäki… - BMC clinical …, 2011 - Springer
… for Ki-67, digitized with a whole slide scanner and uploaded … assembled by the use of
tissue microarray technology [18]. … of Ki-67 staining determined by automated image analysis

[HTML][HTML] Practical approaches to automated digital image analysis of Ki-67 labeling index in 997 breast carcinomas and causes of discordance with visual assessment

AY Kwon, HY Park, J Hyeon, SJ Nam, SW Kim… - PLoS …, 2019 - journals.plos.org
… of staining, labeling or whole slides. We used ADIA for breast cancer evaluation for about
seven months… Through that experience, we recognized the practical limitations of ADIA use. …

[HTML][HTML] Automated quantitative analysis of Ki-67 staining and HE images recognition and registration based on whole tissue sections in breast carcinoma

M Feng, Y Deng, L Yang, Q Jing, Z Zhang, L Xu… - Diagnostic …, 2020 - Springer
… We marked 1017 breast IDC whole slide imaging (WSI), … J (an open source software for digital
pathology image analysis) to … In addition, we provide these digital images of Ki-67 staining

[HTML][HTML] Visual and digital assessment of Ki-67 in breast cancer tissue-a comparison of methods

AH Skjervold, HS Pettersen, M Valla, S Opdahl… - Diagnostic …, 2022 - Springer
… suggested the use of automated digital image analysis (DIA) … using Hamamatsu NanoZoomer
S360 Digital Slide scanner … or tumor stroma cell nuclei) in the whole slide images (WSI). …

Digital quantification of KI-67 in breast cancer

M del Rosario Taco Sanchez, T Soler-Monsó, A Petit… - Virchows Archiv, 2019 - Springer
… generation image analysis. Whole-slide imaging systems convert glass slides into diagnostic
quality … methods, the eyeballing visual assessment on the microscope and the digital image

[HTML][HTML] Digital image analysis of Ki67 proliferation index in breast cancer using virtual dual staining on whole tissue sections: clinical validation and inter-platform …

T Koopman, HJ Buikema, H Hollema… - Breast cancer research …, 2018 - Springer
… a manual whole section scoring protocol with automated … Adjacent sections were stained for
Ki67 (CONFIRM anti-Ki-67 (30-9… The algorithms were then set to use the cytokeratin-stained

[HTML][HTML] A comparison of visual assessment and automated digital image analysis of Ki67 labeling index in breast cancer

F Zhong, R Bi, B Yu, F Yang, W Yang, R Shui - PloS one, 2016 - journals.plos.org
… spectrum of staining seen on initial overview of the whole slide. In … of Ki67 LI assessment,
with benefits of increased capacity, … Ki-67 as prognostic marker in early breast cancer: a meta-…

[HTML][HTML] Ki67 reproducibility using digital image analysis: an inter-platform and inter-operator study

B Acs, V Pelekanou, Y Bai, S Martinez-Morilla… - Laboratory …, 2019 - Elsevier
… Two breast cancer patient cohorts were used for this study. The … cut and stained for Ki67. The
outcome cohort was from 149 … improved capacity and automation in biomarker evaluation [9…

Proliferation assessment in breast carcinomas using digital image analysis based on virtual Ki67/cytokeratin double staining

R Røge, R Riber-Hansen, S Nielsen… - Breast cancer research and …, 2016 - Springer
… -stained slide where the automated image analysis detects positive areas (tumor cells) and
mark these (green line) as the region of interest. Right tile: Ki67-stained slide … the importance