BRIE: transcriptome-wide splicing quantification in single cells
Y Huang, G Sanguinetti - Genome biology, 2017 - Springer
… splicing across a population of single cells, but as far as we are aware, BRIE is the first
method to be able to quantify splicing in individual single cells and to detect differential splicing …
method to be able to quantify splicing in individual single cells and to detect differential splicing …
Transcriptome-wide splicing quantification in single cells
Y Huang, G Sanguinetti - bioRxiv, 2017 - biorxiv.org
… to quantify alternative splicing in individual cells would … splicing across a population of
single cells, but as far as we are aware BRIE is the first method to be able to quantify splicing …
single cells, but as far as we are aware BRIE is the first method to be able to quantify splicing …
BRIE2: computational identification of splicing phenotypes from single-cell transcriptomic experiments
Y Huang, G Sanguinetti - Genome biology, 2021 - Springer
… of splicing phenotypes within the splicing quantification task … the splicing ratio from a set
of features associated with cell-… By default in brie-quant, we filter out events with (1) less than …
of features associated with cell-… By default in brie-quant, we filter out events with (1) less than …
Computational identification of splicing phenotypes from single cell transcriptomic experiments
Y Huang, G Sanguinetti - biorxiv, 2020 - biorxiv.org
… of splicing phenotypes within the splicing quantification task itself… the splicing ratio from a set
of features associated with cell-… By default in brie-quant, we filter out events with 1) less than …
of features associated with cell-… By default in brie-quant, we filter out events with 1) less than …
[HTML][HTML] Single-cell alternative splicing analysis reveals dominance of single transcript variant
W Liu, X Zhang - Genomics, 2020 - Elsevier
… single cells tend to express one major transcript variant of a gene, and the diversity of transcript
variants in cell … Therefore, we believe that BRIE is not suitable for testing the cell model …
variants in cell … Therefore, we believe that BRIE is not suitable for testing the cell model …
Using BRIE to detect and analyze splicing isoforms in scRNA-Seq data
Y Huang, G Sanguinetti - … Methods for Single-Cell Data Analysis, 2019 - Springer
… BRIE, the first and one of the very few methods for splicing quantification from scRNA-seq
[20]. … In order to quantify the exon-skipping splicing with BRIE, we need a set of good quality …
[20]. … In order to quantify the exon-skipping splicing with BRIE, we need a set of good quality …
[HTML][HTML] Technological advances and computational approaches for alternative splicing analysis in single cells
WX Wen, AJ Mead, S Thongjuea - Computational and structural …, 2020 - Elsevier
… the first time, characterization of transcriptome-wide exon-level alternative splicing events at
the … In addition to characterizing exclusion and inclusion rates across identical cells, BRIE is …
the … In addition to characterizing exclusion and inclusion rates across identical cells, BRIE is …
[PDF][PDF] Single-cell transcriptomic analysis reveals dynamic alternative splicing and gene regulatory networks among pancreatic islets
Y Li, J Chen, Q Xu, Z Han, F Tan, T Shi… - Science China Life …, 2021 - researchgate.net
… Figure 1 Alternative splicing and gene regulatory network profiles of pancreatic islet … BRIE:
transcriptome-wide splicing quantification in single cells. Genome Biol 18, 123. Lee, Y., and …
transcriptome-wide splicing quantification in single cells. Genome Biol 18, 123. Lee, Y., and …
MARVEL: an integrated alternative splicing analysis platform for single-cell RNA sequencing data
WX Wen, AJ Mead, S Thongjuea - Nucleic Acids Research, 2023 - academic.oup.com
… analyze splicing dynamics at single-cell resolution. Here, we present MARVEL, a comprehensive
R package for single-cell splicing analysis … For BRIE, differential splicing analysis was …
R package for single-cell splicing analysis … For BRIE, differential splicing analysis was …
Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity
… The following settings were used to quantify splicing with BRIE: exons have to be located
on autosomes and input chromosomes and should not be overlapped by any other …
on autosomes and input chromosomes and should not be overlapped by any other …