Disruption of mitochondrial redox circuitry in oxidative stress

DP Jones - Chemico-biological interactions, 2006 - Elsevier
… considers oxidative stress as a disruption of mitochondrial redox … Mitochondria contain
two types of redox circuits, high-flux … redox systems for protection against oxidative stress. …

[HTML][HTML] The system biology of thiol redox system in Escherichia coli and yeast: differential functions in oxidative stress, iron metabolism and DNA synthesis

MB Toledano, C Kumar, N Le Moan, D Spector… - FEBS letters, 2007 - Elsevier
… regulating the biological functions it subserves. Here, we consider the thiol redox systems of
… of the cellular functions of these systems. We show that although prokaryotic and eukaryotic …

[PDF][PDF] Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues

J Fujii, Y Iuchi, S Matsuki, T Ishii - Asian journal of andrology, 2003 - Citeseer
… The significance of antioxidant and redox systems in the physiology and pathophysiology of
… and redox systems that are currently assumed to play roles in the male reproductive system. …

Reactive oxygen species, cellular redox systems, and apoptosis

ML Circu, TY Aw - Free radical biology and medicine, 2010 - Elsevier
… NADPH/NADP + are also linked to oxidative stress defense and redox regulation. However,
more versatile biological functions have been attributed to these molecules. For instance, …

[PDF][PDF] ROS function in redox signaling and oxidative stress

M Schieber, NS Chandel - Current biology, 2014 - cell.com
redox biology. In this review we discuss the two faces of ROS — redox biology and oxidative
stress — … Redox biology involves a small increase in ROS levels that activates signaling …

Understanding diversity in oxidative status and oxidative stress: the opportunities and challenges ahead

D Costantini - Journal of Experimental Biology, 2019 - journals.biologists.com
… a biological definition of oxidative stress. From this point of view, one may consider biological
oxidative stress to be any change in one of the molecular components of the redox system

Role of metabolic H2O2 generation: redox signaling and oxidative stress

H Sies - Journal of Biological Chemistry, 2014 - ASBMB
… Metabolically generated H 2 O 2 emerged from recent research as a central hub in redox
signaling and oxidative stress. Upon generation by major sources, the NADPH oxidases or …

Oxidative stress, redox, and the tumor microenvironment

JA Cook, D Gius, DA Wink, MC Krishna, A Russo… - Seminars in radiation …, 2004 - Elsevier
… the generation of energy in biological systems; however, as a … high levels of ROS induce
oxidative stress. ROS are also … , the cellular redox system may be an important system to …

Oxidative stress, redox regulation and diseases of cellular differentiation

ZW Ye, J Zhang, DM Townsend, KD Tew - Biochimica et Biophysica Acta …, 2015 - Elsevier
… Chemical, and for our purposes biological, conversion of oxygen or nitrogen can lead to the
production of reactive oxygen species (ROS) or reactive nitrogen species (RNS), families of …

Oxidative stress and cancer: the role of redox regulation

S Toyokuni - Biotherapy, 1998 - Springer
Oxidative stress in tumor biology The research history of oxidative stress in carcinogenesis …
However, the research on oxidative stress in tumor biology has just begun in the late 80’s. …