Role of metabolic H2O2 generation: redox signaling and oxidative stress
H Sies - Journal of Biological Chemistry, 2014 - ASBMB
… Metabolically generated H 2 O 2 emerged from recent research as a central hub in redox
signaling and oxidative stress. Upon generation by major sources, the NADPH oxidases or …
signaling and oxidative stress. Upon generation by major sources, the NADPH oxidases or …
Biochemistry of oxidative stress
H Sies - Angewandte Chemie International Edition in English, 1986 - Wiley Online Library
… oxidative reactions. Oxidative damage inflicted by reactive oxygen species has been called
“… This review article is concerned with oxidative damage in biological systems. First of all, the …
“… This review article is concerned with oxidative damage in biological systems. First of all, the …
[HTML][HTML] Oxidative stress
GJ Burton, E Jauniaux - Best practice & research Clinical obstetrics & …, 2011 - Elsevier
… potentially damaging side-effects for biological systems. Reactivity allows oxygen to participate
… Free radicals can be generated from many elements, but in biological systems it is those …
… Free radicals can be generated from many elements, but in biological systems it is those …
On the history of oxidative stress: Concept and some aspects of current development
H Sies - Current Opinion in Toxicology, 2018 - Elsevier
… Oxidative stress as a concept in redox biology and medicine has witnessed fulminant
development of the past 30-odd years. It is a global concept, defined as “an imbalance between …
development of the past 30-odd years. It is a global concept, defined as “an imbalance between …
Iron, oxidative stress, and redox signaling in the cardiovascular system
A Gudjoncik, C Guenancia, M Zeller… - Molecular nutrition & …, 2014 - Wiley Online Library
… The respiratory chain relies on iron-containing redox systems in the form of complexes I–III
with Fe–S clusters and cytochromes with heme as prosthetic groups. As we previously …
with Fe–S clusters and cytochromes with heme as prosthetic groups. As we previously …
Oxidative stress and antioxidants: biological response modifiers of oxidative homeostasis in cancer
A Čipak Gašparović, T Lovaković, N Žarković - Periodicum biologorum, 2010 - hrcak.srce.hr
… Oxidative stress is defined as a misbalance in cell redox reactions resulting in the increase
… /or decreased antioxidant defence. Crucial part of oxidative stress, which avoids protective ef…
… /or decreased antioxidant defence. Crucial part of oxidative stress, which avoids protective ef…
Oxidative stress and cancer: the role of redox regulation
S Toyokuni - Biotherapy, 1998 - Springer
… Oxidative stress in tumor biology The research history of oxidative stress in carcinogenesis …
However, the research on oxidative stress in tumor biology has just begun in the late 80’s. …
However, the research on oxidative stress in tumor biology has just begun in the late 80’s. …
[PDF][PDF] What is oxidative stress?
T Yoshikawa, Y Naito - Japan medical association journal, 2002 - Citeseer
… Many of the genes that are associated with biological oxidative stress have been identified,
with the genes for NO synthetase (NOS) and heme oxygenase (HO) being considered as …
with the genes for NO synthetase (NOS) and heme oxygenase (HO) being considered as …
[PDF][PDF] Some current insights into oxidative stress.
Z Ďuračková - Physiological research, 2010 - researchgate.net
… and they prevent oxidation of biologically important molecules by FR or RM. (c) If protection
of the organism fails at this level, then repair systems recognize impaired molecules and …
of the organism fails at this level, then repair systems recognize impaired molecules and …
Redox proteomics: chemical principles, methodological approaches and biological/biomedical promises
A Bachi, I Dalle-Donne, A Scaloni - Chemical reviews, 2013 - ACS Publications
… responses to oxidative stress are often mediated by redox-… , whose redox-active cysteine
residues are targets for redox … both redox systems, the high ratios of reduced to oxidized form …
residues are targets for redox … both redox systems, the high ratios of reduced to oxidized form …