… to promote HTLV-1 binding to cells … HTLV-1 cell tropism. It also remains to be more definitively
proven that these molecules are sufficient to permit HTLV-1 entry into completely HTLV-1…

… described to be critical for HTLV-1 transmission, tight junctions and cellular conduits. Further,
… receptor on the uninfected cell, viral particles cross the VS and enter the uninfected cell [61,…

… retroviruses, HTLV-1 and HTLV-2 enter target cells following specific interactions between
the viral envelope glycoprotein (Env) and cellular receptors. Efficient entry of HTLV-1 has …

… Interactions with these factors are responsible for HTLV-1 LTR-trans-activation, as well as
the activation of certain proliferative genes during cellular transformation. The dimerization …

… , which is typically associated only with HTLV-1 infection, … proteins in HTLV-1 infectivity
and pathogenicity. p8 and p12, … early steps of infection, at the entry step, the tropism is almost …

… HTLV-1 life cycle: HTLV-1 virion interacts with the target cell surface receptors GLUT1/
HSPG/NRP-1 via the HTLV-1 … viruses enter the synaptic cleft and interact with cellular receptors. …

… associated HTLV-1 viral particles fuse with the plasma membrane of target cells, or are
internalized and enter … whether this cellular model reflects the cell-to-cell transmission of HTLV-1, …

… HTLV-1 recruits many cellular and viral genes and form a protein ring in the … entry and
effective virus dissemination, and promote tissue damages involved in the HAM/TSP pathogenicity…

… HTLV-1 is dependent on cellular factors for the initial rounds … HTLV-1 and HTLV-2 display
differences in pathogenicity, … of the viral and cellular membranes, facilitating viral entry. Binding …

… HTLV-1) infection is associated with adult T-cell leukemia/lymphoma (ATL). Tropical spastic
paraparesis/HTLV-1-associated myelopathy (PET/HAM) is involved … development of HTLV-1-…