ChABC-loaded PLGA nanoparticles: A comprehensive study on biocompatibility, functional recovery, and axonal regeneration in animal model of spinal cord injury
… regeneration of injured neurons (Emma et al., 2001). In this study, we produced the
ChABC-loaded PLGA nanoparticles … to achieve better axonal regeneration and functional …
ChABC-loaded PLGA nanoparticles … to achieve better axonal regeneration and functional …
Combined Delivery of Chondroitinase ABC (ChABC) and Stromal Cell Derived Factor 1α (SDF1α) for Spinal Cord Regeneration
MM Pakulska - 2016 - tspace.library.utoronto.ca
… that can provide functional recovery. SCI … after spinal cord injury. Application of this enzyme
has been found to increase axonal regeneration and plasticity after SCI in animal models, …
has been found to increase axonal regeneration and plasticity after SCI in animal models, …
[HTML][HTML] Sustained delivery of chABC improves functional recovery after a spine injury
A Sharifi, A Zandieh, Z Behroozi, MR Hamblin… - BMC neuroscience, 2022 - Springer
… the efficiency of functional recovery after SCI in animal models (… also biocompatible and
biodegradable [45,46,47]. In various … on neuronal regeneration and functional recovery [60, 65]. …
biodegradable [45,46,47]. In various … on neuronal regeneration and functional recovery [60, 65]. …
Injectable scaffold-systems for the regeneration of spinal cord: advances of the past decade
S Santi, I Corridori, NM Pugno, A Motta… - … Science & Engineering, 2021 - ACS Publications
… procedures are preferred to treat spinal cord injuries (SCI), … results: axon elongation, functional
recovery, suppression of the … used for validating axonal regeneration, but this model is far …
recovery, suppression of the … used for validating axonal regeneration, but this model is far …
Sustained dual drug delivery of anti-inhibitory molecules for treatment of spinal cord injury
TS Wilems, SE Sakiyama-Elbert - Journal of Controlled Release, 2015 - Elsevier
… and limit functional recovery. The NEP1-40 peptide … greatly limits axonal regeneration into
and across the injury site. … -40 loaded PLGA microspheres or 5 mg of FITC-ChABC loaded …
and across the injury site. … -40 loaded PLGA microspheres or 5 mg of FITC-ChABC loaded …
[HTML][HTML] Novel strategies for spinal cord regeneration
B Costăchescu, AG Niculescu, MG Dabija… - International Journal of …, 2022 - mdpi.com
… for spinal cord repair, functional recovery, and axonal … regeneration, being a promising
biocompatible material for … a permissive microenvironment for axonal regeneration. The natural …
biocompatible material for … a permissive microenvironment for axonal regeneration. The natural …
[HTML][HTML] Recent advances in the combination of cellular therapy with stem cells and nanoparticles after a spinal cord injury
E García, S Sánchez-Noriega… - Frontiers in …, 2023 - frontiersin.org
… In addition, NM-formed NPs are able to restore axonal regeneration with regard to promoting
… with NPs ChABC-loaded PLGA and a significant therapeutic effect on functional recovery (…
… with NPs ChABC-loaded PLGA and a significant therapeutic effect on functional recovery (…
[HTML][HTML] The Translation of Nanomedicines in the Contexts of Spinal Cord Injury and Repair
W Wang, J Yong, P Marciano, R O'Hare Doig, G Mao… - Cells, 2024 - mdpi.com
… of the nanoparticle (NP) biocompatibility–neurotoxicity … improve functional recovery in rats
with complete spinal cord injury… dust worsened the outcome of SCI in animal models. However, …
with complete spinal cord injury… dust worsened the outcome of SCI in animal models. However, …
A systematic review and meta-analysis of chondroitinase ABC promotes functional recovery in rat models of spinal cord injury
Y Zhang, R Xue, M Yao, Z Li, C Hu, Y Dai… - Nutritional …, 2023 - Taylor & Francis
… described calculation of sample size, or whether animal models were affected by diabetes,
… for the observation of glial scar and axonal regeneration after SCI. Meta-analysis results …
… for the observation of glial scar and axonal regeneration after SCI. Meta-analysis results …
Nanoparticle technologies in the spinal cord
JM Zuidema, RJ Gilbert, DJ Osterhout - Cells Tissues Organs, 2016 - karger.com
… Clinical uses of QDs are limited until more biocompatible … potentially function to both
stimulate and guide axon regrowth … The chABC-loaded nanoparticles release active enzyme …
stimulate and guide axon regrowth … The chABC-loaded nanoparticles release active enzyme …