… to mood syndromes. Here, we outline evidence for a new … phenotype, which we have called
‘circadian depression’. We propose that key clinical characteristics of circadian depression …

… Circadian rhythms are associated with various human states, especially mood disorders,
and disturbance of the circadian … with mood disorders (major depressive disorder [MDD] and …

… aetiology between circadian disruption and depression, although … in depression, with an
emphasis on circadian genes. … gene and circadian phenotypes typical of bipolar disorder (table II…

… of the circadian clock, physiological regulation by the circadian … the circadian clock and
mood disorders such as depression, but … with disrupted circadian rhythms on depression-related …

… associated with mood disorders, including seasonal affective disorder and major … depressive
episode is ∼17% in the US (25), and because patients with depression manifest circadian …

… In one example, a chronic social defeat paradigm led to a depressive-like phenotype in
some mice but not others, which is accompanied by altered biological rhythms only in the …

… populations at high risk for depression and related mood disorders. Although this study
cannot disentangle causal relationships between circadian phenotypes and negative affect, we …

… of the circadian neural and genetic mechanisms underlying mood … for the cure of depression
and other mood disorders. … were correlated with circadian phenotypes and mood in a group …

… to their previously reported involvement in MD or circadian phenotypes in the literature, and
9 … All genotyping was performed blind with respect to phenotype. Details of the quality control …

… by episodes of depressed mood, whereas BD includes both depressive episodes and …
cells in circadian clock phenotyping. In the healthy state, peripheral and SCN phenotypes are …