Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: a critical multi‐disciplinary literature review and agenda for future …

MJ McCarthy, JF Gottlieb, R Gonzalez… - … disorders, 2022 - Wiley Online Library
… definition of the BD phenotype, accepted all measures and proxies of circadian function,
and … It has been hypothesized that circadian disruption may trigger first manic or depressive

[HTML][HTML] Digital phenotype of mood disorders: A conceptual and critical review

R Maatoug, A Oudin, V Adrien, B Saudreau… - Frontiers in …, 2022 - frontiersin.org
… the digital phenotypes of several mood disorders using machine … phenotype of mood disorders
(depressive disorder and … digital phenotypes into 130 features based on circadian rythms (…

[HTML][HTML] Circadian biology to advance therapeutics for mood disorders

A Bhatnagar, G Murray, S Ray - Trends in Pharmacological Sciences, 2023 - cell.com
… , cell lines derived from mood disorder patients, and clinical … between circadian function
and mood disorder phenotypes. … For example, diurnal variation of depressive symptoms is a …

Using chronobiological phenotypes to address heterogeneity in bipolar disorder

R Gonzalez, SD Gonzalez, MJ McCarthy - Molecular neuropsychiatry, 2020 - karger.com
… episodes of mania and depression in addition to … to the circadian clock, and pre-sent recent
studies that evaluated chronobiological measures as a basis for establishing BD phenotypes. …

[HTML][HTML] Clinical subtypes of depression are associated with specific metabolic parameters and circadian endocrine profiles in women: the power study

G Cizza, DS Ronsaville, H Kleitz, F Eskandari, S Mistry… - PloS one, 2012 - journals.plos.org
… A leptin hypothesis linking mood disorder and obesity, two … phenotypic differences in
clinical subtypes, the sample size was uneven among groups. The current analysis of phenotypic

Prevalence of circadian misalignment and its association with depressive symptoms in delayed sleep phase disorder

JM Murray, TL Sletten, M Magee, C Gordon, N Lovato… - Sleep, 2017 - academic.oup.com
depressive symptoms, providing further evidence for a circadian basis for mood disturbances
(Criterion A), 32 our definition of circadian DSPD phenotype was based on the timing of the …

Prediction of impending mood episode recurrence using real-time digital phenotypes in major depression and bipolar disorders in South Korea: a prospective …

HJ Lee, CH Cho, T Lee, J Jeong, JW Yeom… - Psychological …, 2023 - cambridge.org
… pathophysiological mechanism of mood disorders (Moon et al., 2016) our results showed
that parameters related to circadian misalignment predicted the onset of mood episodes. Such …

Circadian phenotype in patients with the co-morbid alcohol use and bipolar disorders

T Hätönen, S Forsblom, T Kieseppä… - Alcohol & …, 2008 - academic.oup.com
… Since data on the circadian phenotype of patients with bipolar disorder are still scarce, we
… co-morbid alcohol use disorder to provide information about their circadian-type preference. …

[HTML][HTML] Circadian rhythms and psychiatric profiles in young adults with unipolar depressive disorders

R Robillard, JS Carpenter, NL Rogers, S Fares… - Translational …, 2018 - nature.com
… Longitudinal studies are required to determine the relationship between circadian profiles
and the course of illness of mood disorders. Pharmacological, environmental, or behavioural …

Circadian rhythm sleep–wake disturbances and depression in young people: implications for prevention and early intervention

JJ Crouse, JS Carpenter, YJC Song, SJ Hockey… - The Lancet …, 2021 - thelancet.com
depression and circadian dysrhythmias, with a primary focus on circadian rhythm sleep–wake
disturbances … phase of bipolar disorder (henceforth referred to as bipolar depression), and …