Computational approaches from polymer physics to investigate chromatin folding
… and have proved to be an important tool to investigate chromatin folding (Figure 1). Here, we
… point of view of polymer physics modeling, focusing on principled approaches, in particular, …
… point of view of polymer physics modeling, focusing on principled approaches, in particular, …
A modern challenge of polymer physics: novel ways to study, interpret, and reconstruct chromatin structure
… applications of these computational approaches, we … the chromatin is a polymer, we expect
that its folding properties can be quantitatively studied in the framework of polymer physics. In …
that its folding properties can be quantitatively studied in the framework of polymer physics. In …
Efficient computational implementation of polymer physics models to explore chromatin structure
M Conte, A Esposito, L Fiorillo… - … Journal of Parallel …, 2022 - Taylor & Francis
… on Polymer Physics to describe the chromatin architecture, clarifying many aspects about the
molecular mechanisms underlying genome folding… some general computational methods to …
molecular mechanisms underlying genome folding… some general computational methods to …
Understanding chromatin structure: Efficient computational implementation of polymer physics models
S Bianco, C Annunziatella, A Esposito, L Fiorillo… - Euro-Par 2018: Parallel …, 2019 - Springer
… 2, we will describe some general computational methods to … of High Performance Computing
(HPC) resources to fully explore the … properties of chromatin and explain the folding of real …
(HPC) resources to fully explore the … properties of chromatin and explain the folding of real …
[HTML][HTML] The physics of DNA folding: polymer models and phase-separation
… computational approaches showing the versatility of polymer models to tackle the problem of
chromatin folding in general and to study … specific applications of polymer physics models to …
chromatin folding in general and to study … specific applications of polymer physics models to …
[HTML][HTML] Unveiling the Machinery behind Chromosome Folding by Polymer Physics Modeling
… of chromatin organization: loop-extrusion and polymer phase-… In the last years, many different
computational strategies have … Finally, we examine the molecular determinants of folding …
computational strategies have … Finally, we examine the molecular determinants of folding …
Polymer models for the mechanisms of chromatin 3D folding: review and perspective
R Zhou, YQ Gao - Physical Chemistry Chemical Physics, 2020 - pubs.rsc.org
… due to the high expense of computation. In this review, we … However, classical polymer
physics proposes a power-law … This study questioned the assumption that CTCF alone could …
physics proposes a power-law … This study questioned the assumption that CTCF alone could …
Computational strategies to address chromatin structure problems
… approaches in the chromatin structure field with an emphasis on modeling, such as molecular
dynamics and coarse-grained computational approaches… to explore the protein folding and …
dynamics and coarse-grained computational approaches… to explore the protein folding and …
Polymer models are a versatile tool to study chromatin 3D organization
… To highlight the potentialities of such kind of computational approaches, here we discuss …
approaches, such as models from polymer physics, are crucial to investigate chromatin folding …
approaches, such as models from polymer physics, are crucial to investigate chromatin folding …
How the genome folds: the biophysics of four-dimensional chromatin organization
… by computational modeling efforts based on polymer physics … from polymer physics relevant
to DNA and chromatin, then … Figure 3 Techniques to study chromatin organization fall into …
to DNA and chromatin, then … Figure 3 Techniques to study chromatin organization fall into …