… reviewed the most current advances to elucidate the etiological factors and therapeutic
targets that could provide better strategies for the management of APAP-induced hepatotoxicity. …

… novel therapeutic strategies. This work summarizes the important cellular events involved in
AIH and discusses potential therapeutic targets … use, as well current treatment limitations, the …

… not fully understood, while the comprehension of the cellular process behind APAP-induced …
relationship is present, is the hepatotoxicity potential of the potential causative agents. The …

… Finally, we describe the current potential treatment options for AILI patients and promising
… to guide drug screening and selection for the clinical treatment of AILI patients in the future. …

… In this review, we present how OTC and prescription … NAC therapy is that it is not used for
acetaminophen-induced … on their use as potential therapeutic targets in DILI. Acute DILI is …

… The specificity of miRNAs is organ specific but not etiology specific. For example, in acute …
, thereby upregulating its target CES2 that detoxifies APAP. It is hard to comprehend that CES2 …

… to the comprehension and possible avoidance of drug-induced … The importance of etiological
diagnosis cannot be over… to the course of acetaminophen-induced toxicity, we compared tox…

… and emphasize the currently available scientific evidence to … , and ruling out alternative
etiologies of liver injury. The capacity of … Further comprehension of insights into the underlying …

… and elimination, which comprehend drugs and toxins, among … the recent novelties achieved
in the treatment of chronic viral … hepatitis B virus continue to be the most common etiologies …

… explored in alleviating acetaminophen-induced liver injury. They … etiologies that lead to
multiple forms of drug-induced … causing hepatotoxicity, highlighting the need to comprehend drug …