… against colorectal tumor development seems to be related particularly to cyclooxygenase-2
(… NSAIDs, might be effective for colorectal cancer prevention and treatment. However, COX-2 …

… colorectal cancer have not been fully understood. For example, cyclooxygenase-2 (COX-2)
and its … ) have been closely linked to its occurrence, progression and prognosis. However, the …

… progression of colorectal cancer; however, the detailed mechanism of its role in causing
colorectal cancer … In addition, the role of COX-2 signaling through the interaction in the epithelial …

… in colorectal cancer varies among tumors and the extent of COX-2 staining correlates with a
poorer prognosis. The colorectal cancer … patients presenting with colorectal tumors to a large …

… effectively prevent experimental colon cancer and can regress colorectal polyps in patients
… the role of COX-2 as a target for the prevention and treatment of human colorectal cancer. © …

… , the role of cyclooxygenase-2 expression in colorectal cancer … cyclooxygenase-2 expression
in human colorectal cancer. METHODS: A total of 232 surgically resected colorectal cancer …

… Therefore, to clarify additionally the prognostic role of Cox-2 in colorectal carcinoma and to
… both proteins in a series of patients with primary tumors, who were treated at our institution. In …

… Cancer Epidemiol Biomarkers Prev 2007; 15: 185–187. 25 Bertagnolli MM: Chemoprevention
of colorectal cancer with cyclooxygenase-2 inhibitors: two steps forward, one step back. …

… 2 ) in colorectal carcinogenesis. Recently, cyclooxygenase 2 (COX-2) which catalyses the
… of arachidonic acid to PGE 2 , has displayed increased levels in human colorectal cancer. …

… the role of COX-2 in colorectal cancer progression in various clinical studies which are associated
with sporadic cancer, … and Hereditary nonpolyposis colorectal cancer. Furthermore, we …