Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice

CH Niu, Y Wang, JD Liu, JL Wang, JH Xiao - European journal of …, 2013 - Elsevier
… observed in the prednisolone or pirfenidone treated mice. In … +CD25+ Tregs which may
modulate Th1/Th2 imbalance by … by the cytokines profiled with dominance of IL-4 over IFN-γ, ie…

Molecular targets in pulmonary fibrosis: the myofibroblast in focus

CJ Scotton, RC Chambers - Chest, 2007 - Elsevier
… T-helper type 1/Th2 cytokine expression, with Th2 cytokines … In mice, daily treatment with
IFN-γ following bleomycin injury … 40 in IPF patients who had failed to respond to corticosteroids. …

[HTML][HTML] Characterization of CD28null T cells in idiopathic pulmonary fibrosis

DM Habiel, MS Espindola, C Kitson, AV Azzara… - Mucosal …, 2019 - Elsevier
… elevation of pro-inflammatory cytokine expression in IPF relative … of IPF CD28 null T cells to
corticosteroids, 2 × 10 5 IPF1 T … -1 might protect against fibrosis in IPF via its modulation of T …

Idiopathic pulmonary fibrosis: emerging concepts on pharmacotherapy

VJ Thannickal, KR Flaherty, FJ Martinez… - Expert Opinion on …, 2004 - Taylor & Francis
corticosteroid/immunosuppressive agents will be briefly reviewed, and then emerging
new therapies designed to modulateIFN-γ is an immunoregulatory cytokine pivotal in host …

Studies of cytokine levels in bronchoalveolar fluid lavage from patients with interstitial lung diseases

H Wolff, AM TEPPO, P Mutanen, S Sutinen… - … Journal of Clinical …, 2003 - Taylor & Francis
… or treatment with immunosuppressive drugs (oral, injected and inhaled corticosteroids or …
Platelet-derived growth factor-BB (PDGF-BB) in tear fluid—a potential modulator of corneal …

The clinical and immunologic features of pulmonary fibrosis in sarcoidosis

KC Patterson, K Hogarth, AN Husain, AI Sperling… - Translational …, 2012 - Elsevier
… , in addition to modulation from other cytokine signal inputs, … cytokine signature, including
the upregulation of IFN-γ, the … Systemic corticosteroids are associated with substantial side …

Immune cells crosstalk Pathways, and metabolic alterations in Idiopathic pulmonary fibrosis

P Tiwari, S Verma, KR Washimkar… - International …, 2024 - Elsevier
… cell modulation holds promise in managing pulmonary fibrosis (PF). … of cytokines like IFN-γ
and IL-12, demonstrate anti-fibrotic … Anti-inflammatory therapies, such as corticosteroids, have …

“End‐stage” Pulmonary Fibrosis in Sarcoidosis

AT Teirstein, AS Morgenthau - … Journal of Medicine: A Journal of …, 2009 - Wiley Online Library
1 (Th1) cytokines [interferon-γ (IFN-γ)], IL-2, or T helper 2 (Th2) … suggest that IFN-γ –induced
CXC chemokines modulatecorticosteroid or immunosuppressive treatment of fibrotic lung …

Determinants of initiation and progression of idiopathic pulmonary fibrosis

RM Kottmann, CM Hogan, RP Phipps, PJ Sime - Respirology, 2009 - Wiley Online Library
… and in patients who have been treated with corticosteroids, … -inflammatory cytokine that is
upregulated in pulmonary fibrosis. … These animal models suggest that modulating fibrocyte …

26. Immunomodulation and immunotherapy: drugs, cytokines, cytokine receptors, and antibodies

RP Nelson Jr, M Ballow - Journal of allergy and clinical immunology, 2003 - Elsevier
… , which may permit selective modulation of immunologic balance … possess potent
immunosuppressive activities that make them … as a treatment for steroid-refractory acute GVHD …