… sensitivity of Plasmodium falciparum to chloroquine, quinine … in Lambaréné, Gabon every
second year from 1992 to 1998. We … However, parasite resistance to chloroquine decreased …

… falciparum in vitro has been carried out since 1992 using the WHO standard microtest. … The
apparent decrease of chloroquine resistance in the area of Lambarene has to be interpreted …

… falciparum chloroquine resistance (Pfcrt) genes. The aim of this … on the malaria decline. The
latest WHO report attributed the … in Lambaréné (about 7%), a town situated in the centre of …

… for treating schoolchildren from the Lambarene area with P. … , from 1998 to 2001, a twice-weekly
prophylaxis with chloroquine … falciparum may have lead to decreased activity of quinine …

… , susceptibility to mefloquine and quinine was slightly decreased. A significant increase in
… in Lambarene indicated a marked sensitivity of the parasite to halofantrine in Gabon in 1992.…

… falciparum isolates in Lambaréné, Gabon by measuring … 3D7 (chloroquine sensitive), 7G8
(chloroquine resistant), … Conversely, in vitro activity of chloroquine and mefloquine decreased …

… In this investigation the prevalence of the chloroquine resistance (… in the decline of CQR in
these countries and Gabon? … in this analysis of the Lambaréné parasite population. In view of …

… prevalence of chloroquine resistance had decreased. The … The prevalence of the Pfcrt 76T
mutation decreased since … of 92% of 76T was observed in pregnant women with malaria [44]. …

… Plasmodium falciparum multidrug resistance gene 1 (pfmdr1) have been associated with
chloroquine resistance … In the present study, carried out in Lambaréné, Gabon, we investigated …

… falciparum isolates with decreased susceptibility to MQ in … suburb of Dakar, a prevalence
of 92% of was observed for the … A study in Dakar and Mlomp from 1996 to 1998 showed that …